Benzphetamine

27 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Linezolid Injection Acetaminophen And Codeine Morphine Injection Dexlansoprazole Dacomitinib Palonosetron Injection
1 Contraindicated 25 Major 1 Moderate
All (27) Contraindicated (1) Major (25) Moderate (1)

Major

Benzphetamine Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome Details Benzphetamine Omeprazole Gastrobim Explained Increased exposure to amphetamine Details Benzphetamine Amitriptyline Elavil Explained An increased risk of serotonin syndrome Details Benzphetamine Sertraline Explained Increased amphetamine exposure and an increased risk of serotonin syndrome Details Benzphetamine Buprenorphine Belbuca Explained An increased risk of serotonin syndrome Details Benzphetamine Acetazolamide Diamox® Sequels® Increased exposure to amphetamine Details Benzphetamine Abiraterone Abirtega Increased amphetamine exposure and increased risk of serotonin syndrome Details Benzphetamine Butorphanol Injection Butorphic An increased risk of serotonin syndrome Details Benzphetamine Butorphanol Nasal Spray Stadol® NS An increased risk of serotonin syndrome Details Benzphetamine Dacomitinib Vizimpro Increased amphetamine exposure and increased risk of serotonin syndrome Details Benzphetamine Dexlansoprazole Dexilant Increased exposure to amphetamine Details Benzphetamine Dolasetron Anzemet An increased risk of serotonin syndrome Details Benzphetamine Dolasetron Injection Anzemet An increased risk of serotonin syndrome Details Benzphetamine Esomeprazole Nexium Increased exposure to amphetamine Details Benzphetamine Esomeprazole Injection Nexium Increased exposure to amphetamine Details Benzphetamine Fentanyl Transdermal Patch Duragesic® An increased risk of serotonin syndrome Details Benzphetamine Granisetron Transdermal Patch Sancuso An increased risk of serotonin syndrome Details Benzphetamine Granisetron Injection Granisol An increased risk of serotonin syndrome Details Benzphetamine Hydromorphone Injection Dilaudid Increased risk of serotonin syndrome Details Benzphetamine Hydromorphone Rectal available generically Increased risk of serotonin syndrome Details Benzphetamine Lansoprazole Prevacid Increased exposure to amphetamine Details Benzphetamine Lithium Carbonate Lithobid An increased risk of serotonin syndrome Details Benzphetamine Morphine Injection Astramorph® PF Increased risk of serotonin syndrome Details Benzphetamine Nalbuphine Injection Nubain® An increased risk of serotonin syndrome Details Benzphetamine Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.