Bexarotene

86 interactions 92 cited references
Also sold as: Targretin Targretin® Capsules
About Bexarotene

Bexarotene is used to treat cutaneous T-cell lymphoma (CTCL, a type of skin cancer) in people whose disease could not be treated successfully with at least one other medication. Bexarotene is in a class of medications called retinoids. It works by stopping the growth of cancer cells. Read the full Bexarotene drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Rubella Virus Vaccine, Live Ranolazine Bacillus Of Calmette And Guerin Vaccine, Live Mumps Virus Vaccine, Live Measles Virus Vaccine, Live Dengue Tetravalent Vaccine, Live
10 Contraindicated 63 Major 13 Moderate
All (86) Contraindicated (10) Major (63) Moderate (13)

Contraindicated

Bexarotene Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Ranolazine Aspruzyo Reduced ranolazine exposure Details Bexarotene Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Bexarotene Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Bexarotene Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Bexarotene Atogepant Qulipta Reduced atogepant exposure Details Bexarotene Azathioprine Azasan An increased risk of hepatotoxicity Details Bexarotene Cariprazine Vraylar Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Bexarotene Amlodipine Amvaz® Reduced amLODIPine exposure Details Bexarotene Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Bexarotene Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Bexarotene Alfentanil Reduced ALfentanil exposure, reduced efficacy of ALfentanil and an increased risk of a withdrawal syndrome Details Bexarotene Chlortetracycline An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Bexarotene Demeclocycline Declomycin® An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Desogestrel Decreased contraceptive effectiveness Details Bexarotene Dienogest Decreased contraceptive effectiveness Details Bexarotene Doxycycline Acticlate An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Drospirenone Decreased contraceptive effectiveness Details Bexarotene Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Efavirenz Reduced efavirenz exposure with reduced efficacy; reduced bexarotene exposure with reduced efficacy Details Bexarotene Eravacycline Xerava An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Estradiol Delestrogen Decreased contraceptive effectiveness Details Bexarotene Ethinyl Estradiol Decreased contraceptive effectiveness Details Bexarotene Ethynodiol Decreased contraceptive effectiveness Details Bexarotene Etonogestrel Nexplanon Decreased contraceptive effectiveness Details Bexarotene Gemfibrozil Lopid Increased plasma concentrations of bexarotene Details Bexarotene Gestodene Decreased contraceptive effectiveness Details Bexarotene Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bexarotene Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Bexarotene Levonorgestrel After banger Decreased contraceptive effectiveness Details Bexarotene Lumateperone Caplyta Reduced lumateperone exposure Details Bexarotene Lymecycline An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Meclocycline An increased risk of pseudotumor cerebri (benign intracranial hypertension) Details Bexarotene Medroxyprogesterone Amen® Decreased contraceptive effectiveness Details

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