Binimetinib

Name: Binimetinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

15 interactions 28 cited references

Also sold as: Mektovi Mektovi®

About Binimetinib

Binimetinib is a kinase inhibitor used to treat advanced melanoma that has spread or cannot be surgically removed. Read the full Binimetinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live

9 Contraindicated 6 Major

All (15) Contraindicated (9) Major (6)

Major

Binimetinib Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Binimetinib Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Binimetinib Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Binimetinib Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Binimetinib Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Binimetinib Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.