Bisacodyl Rectal

Name: Bisacodyl Rectal Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

18 interactions 58 cited references

Also sold as: Bisac-Evac Bisac-Evac® Suppositories Bisacodyl Uniserts® Dulcolax Dulcolax® Suppositories Fleet® Bisacodyl Enema The Magic Bullet

About Bisacodyl Rectal

Rectal bisacodyl is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Bisacodyl is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movement. Read the full Bisacodyl Rectal drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Licorice Magnesium Sulfate Polyethylene Glycol 3350

3 Major 15 Minor

All (18) Major (3) Minor (15)

Major

Bisacodyl Rectal Licorice Increased risk of hypokalemia Details Bisacodyl Rectal Magnesium Sulfate May increase the risk of mucosal ulceration or ischemic colitis Details Bisacodyl Rectal Polyethylene Glycol 3350 ClearLax Increased risk of mucosal ulceration or ischemic colitis Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.