Brivaracetam Injection

21 interactions 53 cited references
Also sold as: Briviact Briviact®
About Brivaracetam Injection

Brivaracetam injection is used alone and in combination with other medications to control partial onset seizures (seizures that involve only one part of the brain) in adults, children, and infants 1 month of age or older who cannot take oral medication. Brivaracetam is in a class of medications called anticonvulsants.… Read the full Brivaracetam Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ranolazine Alfentanil Amlodipine Atogepant Calcifediol Carbamazepine
1 Contraindicated 16 Major 4 Moderate
All (21) Contraindicated (1) Major (16) Moderate (4)

Major

Brivaracetam Injection Alfentanil Reduced ALfentanil exposure, reduced efficacy of ALfentanil and an increased risk of a withdrawal syndrome Details Brivaracetam Injection Amlodipine Amvaz® Reduced amLODIPine exposure Details Brivaracetam Injection Atogepant Qulipta Reduced atogepant exposure Details Brivaracetam Injection Calcifediol Rayaldee Altered serum levels of calcifediol Details Brivaracetam Injection Carbamazepine Carbatrol Increased carBAMazepine-10,11 epoxide exposure and an increased risk of carBAMazepine toxicity Details Brivaracetam Injection Cariprazine Vraylar Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Brivaracetam Injection Cobicistat Tybost Reduced cobicistat exposure Details Brivaracetam Injection Hydroxychloroquine Plaquenil Impaired antiepileptic activity Details Brivaracetam Injection Lumateperone Caplyta Reduced lumateperone exposure Details Brivaracetam Injection Nifedipine Adalat® Reduced NIFEdipine exposure Details Brivaracetam Injection Oliceridine Olinvyk Reduced oliceridine exposure and reduced efficacy of oliceridine Details Brivaracetam Injection Orlistat Alli Reduced efficacy of anticonvulsant Details Brivaracetam Injection Pimozide An increased risk of seizure Details Brivaracetam Injection Rifampin Rifadin Decreased brivaracetam plasma concentrations Details Brivaracetam Injection Tramadol ConZip Reduced traMADol exposure and reduced efficacy of traMADol Details Brivaracetam Injection Voriconazole Vfend Reduced voriconazole exposure and an reduced efficacy of voriconazole Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.