Budesonide Nasal Spray

221 interactions 609 cited references

Also sold as: Rhinocort Rhinocort® Allergy Spray Rhinocort® Aqua Nasal Spray

About Budesonide Nasal Spray

Budesonide nasal spray is used to relieve sneezing, runny, stuffy, or itchy nose caused by hay fever or other allergies (caused by an allergy to pollen, mold, dust, or pets). Budesonide nasal spray should not be used to treat symptoms (e.g., sneezing, stuffy, runny, itchy nose) caused by the common cold. Budesonide nas… Read the full Budesonide Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Levoketoconazole Ensitrelvir Desmopressin Voxelotor Vonoprazan

4 Contraindicated 178 Major 39 Moderate

All (221) Contraindicated (4) Major (178) Moderate (39)

Major

Budesonide Nasal Spray Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Budesonide Nasal Spray Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Budesonide Nasal Spray Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Budesonide Nasal Spray Itraconazole Sporanox Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Nasal Spray Ivacaftor Kalydeco Increased budesonide exposure Details Budesonide Nasal Spray Ivosidenib Tibsovo Reduced exposure of sensitive CYP3A4 substrates and risk of loss of efficacy Details Budesonide Nasal Spray Ketoconazole Extina Increased budesonide exposure Details Budesonide Nasal Spray Ketoprofen Actron® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Ketorolac Acular Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Larotrectinib Increased sensitive CYP3A4 substrate exposure and increase in the incidence or severity of adverse reactions Details Budesonide Nasal Spray Lefamulin Xenleta Increased sensitive CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related toxicities associated wi... Details Budesonide Nasal Spray Lenacapavir Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of Cushing's syndrome and adrenal suppression Details Budesonide Nasal Spray Letermovir Prevymis Increased budesonide exposure Details Budesonide Nasal Spray Levofloxacin Levaquin An increased risk of tendon rupture Details Budesonide Nasal Spray Lomefloxacin An increased risk of tendon rupture Details Budesonide Nasal Spray Lomitapide Increased budesonide exposure Details Budesonide Nasal Spray Lonafarnib Zokinvy Increased budesonide exposure Details Budesonide Nasal Spray Lornoxicam Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Loxoprofen Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Lumacaftor Reduced exposure to CYP3A substrate Details Budesonide Nasal Spray Lumiracoxib Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Budesonide Nasal Spray Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Budesonide Nasal Spray Maribavir Livtencity Increased budesonide exposure Details Budesonide Nasal Spray Meclofenamate Meclodium® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Mefenamic Acid Ponstel® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Meloxicam Alloxate Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Mitapivat Aqvesme Reduced CYP3A substrate exposure Details Budesonide Nasal Spray Morniflumate Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Moxifloxacin Avelox An increased risk of tendon rupture Details Budesonide Nasal Spray Nabumetone Relafen Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Nadifloxacin An increased risk of tendon rupture Details Budesonide Nasal Spray Nadroparin Increased risk of bleeding Details Budesonide Nasal Spray Naproxen Aleve Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Nefazodone Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Nasal Spray Nelfinavir Viracept Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Nasal Spray Nepafenac Ilevro Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Netupitant Increased exposure of CYP3A4 substrate Details Budesonide Nasal Spray Niflumic Acid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nasal Spray Nilotinib Increased budesonide exposure Details

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