Buprenorphine
633 interactions 533 explained in plain English 652 cited references
Also sold as:
Belbuca
Brixadi
Buprenex
BuTrans
Simbadol
Sublocade
Zorbium
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Buprenorphine Fenfluramine Explained An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Buprenorphine Fentanyl Explained Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Buprenorphine Fesoterodine Toviaz Explained An increased risk of paralytic ileus Details Buprenorphine Fexinidazole Explained An increased risk of QT interval prolongation Details Buprenorphine Fingolimod Gilenya Explained An increased risk of QT interval prolongation Details Buprenorphine Flavoxate Explained An increased risk of paralytic ileus Details Buprenorphine Flecainide Tambocor® An increased risk of QT interval prolongation Details Buprenorphine Flibanserin Addyi Explained An increased risk of respiratory depression and CNS depression Details Buprenorphine Flunitrazepam Explained An increased risk of CNS depression and respiratory depression Details Buprenorphine Fluoxetine RECONCILE Explained An increased risk of QT interval prolongation and an increased risk of serotonin syndrome Details Buprenorphine Fluphenazine Explained An increased risk of respiratory and CNS depression and an increased risk of paralytic ileus Details Buprenorphine Flurazepam Explained An increased risk of CNS depression and respiratory depression Details Buprenorphine Fluspirilene Explained An increased risk of respiratory depression and CNS depression Details Buprenorphine Fluvoxamine Explained An increased risk of serotonin syndrome, increased buprenorphine exposure and an increased risk of buprenorphine-related adverse e... Details Buprenorphine Formoterol Perforomist Explained An increased risk of QT interval prolongation Details Buprenorphine Fosamprenavir Lexiva Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Buprenorphine Fosaprepitant Emend Injection Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Buprenorphine Foscarbidopa Explained An increased risk of CNS depression Details Buprenorphine Foscarnet Foscavir Explained An increased risk of QT interval prolongation Details Buprenorphine Fosfomycin Contepo Explained An increased risk of QT interval prolongation Details Buprenorphine Foslevodopa Explained An increased risk of CNS depression Details Buprenorphine Fosnetupitant Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Buprenorphine Fosphenytoin Cerebyx Explained Reduced buprenorphine exposure, reduced efficacy of buprenorphine and an increased risk of QT interval prolongation Details Buprenorphine Fospropofol Explained An increased risk of respiratory depression and CNS depression Details Buprenorphine Fostemsavir Rukobia Increased risk of torsade de pointes Details Buprenorphine Frovatriptan Frova Explained An increased risk of serotonin syndrome Details Buprenorphine Furosemide Disal Explained Reduced efficacy of diuretics Details Buprenorphine Gabapentin Gabarone Explained An increased risk of respiratory depression and CNS depression Details Buprenorphine Gabapentin Enacarbil Horizant Explained An increased risk of respiratory depression and CNS depression Details Buprenorphine Galantamine Razadyne An increased risk of QT interval prolongation Details Buprenorphine Gatifloxacin Zymaxid Explained An increased risk of QT interval prolongation Details Buprenorphine Gemifloxacin Factive An increased risk of QT interval prolongation Details Buprenorphine Gepirone Exxua Explained Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Buprenorphine Gepotidacin Blujepa Explained An increased risk of QT interval prolongation Details Buprenorphine Givinostat Duvyzat Explained Increased risk of QT interval prolongation and torsade de pointes Details Buprenorphine Glasdegib Daurismo Increased risk of QT interval prolongation Details Buprenorphine Glycopyrrolate Cuvposa Explained An increased risk of paralytic ileus Details Buprenorphine Glycopyrronium Tosylate Explained An increased risk of paralytic ileus Details Buprenorphine Gonadorelin Explained An increased risk of QT interval prolongation Details Buprenorphine Goserelin Explained An increased risk of QT interval prolongation DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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