Calaspargase Pegol-Mknl Injection

Name: Calaspargase Pegol-Mknl Injection Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

15 interactions 19 cited references

Also sold as: Asparlas Asparlas®

About Calaspargase Pegol-Mknl Injection

Calaspargase pegol-mknl is used with other chemotherapy drugs to treat acute lymphocytic leukemia (ALL; a type of cancer of the white blood cells) in infants, children, and young adults aged 1 month to 21 years old. Calaspargase pegol-mknl is an enzyme that interferes with natural substances necessary for cancer cell g… Read the full Calaspargase Pegol-Mknl Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live

9 Contraindicated 6 Major

All (15) Contraindicated (9) Major (6)

Major

Calaspargase Pegol-Mknl Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Calaspargase Pegol-Mknl Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Calaspargase Pegol-Mknl Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Calaspargase Pegol-Mknl Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Calaspargase Pegol-Mknl Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Calaspargase Pegol-Mknl Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.