Cetirizine Ophthalmic

180 interactions 179 cited references

Also sold as: Zerviate Zerviate®

About Cetirizine Ophthalmic

Cetirizine ophthalmic is used to relieve the itching of allergic pink eye. Cetirizine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Read the full Cetirizine Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Isocarboxazid Zuranolone Secobarbital Scopolamine Ropeginterferon Alfa-2B-Njft Remoxipride

1 Contraindicated 175 Major 4 Moderate

All (180) Contraindicated (1) Major (175) Moderate (4)

Major

Cetirizine Ophthalmic Perampanel FYCOMPA Increased risk of CNS depression Details Cetirizine Ophthalmic Perazine Increased risk of CNS depression Details Cetirizine Ophthalmic Periciazine Increased risk of CNS depression Details Cetirizine Ophthalmic Perphenazine Increased risk of CNS depression Details Cetirizine Ophthalmic Phenobarbital Fidoquel Increased risk of CNS depression Details Cetirizine Ophthalmic Pimozide Increased risk of CNS depression Details Cetirizine Ophthalmic Piperacetazine Increased risk of CNS depression Details Cetirizine Ophthalmic Pipotiazine Increased risk of CNS depression Details Cetirizine Ophthalmic Piritramide Increased risk of CNS depression Details Cetirizine Ophthalmic Pitolisant Wakix Reduced efficacy of pitolisant Details Cetirizine Ophthalmic Potassium Oxybate Xywav An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Cetirizine Ophthalmic Prazepam Increased risk of CNS depression Details Cetirizine Ophthalmic Pregabalin Bonqat An increased risk of respiratory depression Details Cetirizine Ophthalmic Primidone Mysoline Increased risk of CNS depression Details Cetirizine Ophthalmic Prochlorperazine Increased risk of CNS depression Details Cetirizine Ophthalmic Promazine Increased risk of CNS depression Details Cetirizine Ophthalmic Promethazine Phenadoz Increased risk of CNS depression Details Cetirizine Ophthalmic Propofol Diprivan Increased risk of CNS depression Details Cetirizine Ophthalmic Quazepam Doral Increased risk of CNS depression Details Cetirizine Ophthalmic Quetiapine Seroquel Increased risk of CNS depression Details Cetirizine Ophthalmic Ramelteon Rozerem Increased risk of CNS depression Details Cetirizine Ophthalmic Remifentanil Increased risk of CNS depression Details Cetirizine Ophthalmic Remoxipride Increased risk of CNS depression Details Cetirizine Ophthalmic Ropeginterferon Alfa-2B-Njft Besremi Increased risk of sedation Details Cetirizine Ophthalmic Scopolamine Pamine Increased or potentiated scopolamine effects and an increased risk of CNS depression Details Cetirizine Ophthalmic Secobarbital Increased risk of CNS depression Details Cetirizine Ophthalmic Sertindole Increased risk of CNS depression Details Cetirizine Ophthalmic Sodium Oxybate Lumryz An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Cetirizine Ophthalmic Sufentanil Dsuvia Reduced pulmonary arterial pressure, increased risk for hypotension, profound sedation, respiratory depression, coma, and death Details Cetirizine Ophthalmic Sulpiride Increased risk of CNS depression Details Cetirizine Ophthalmic Suvorexant Belsomra Increased risk of CNS depression Details Cetirizine Ophthalmic Tapentadol Nucynta Increased risk of CNS depression Details Cetirizine Ophthalmic Temazepam Restoril Increased risk of CNS depression Details Cetirizine Ophthalmic Thiethylperazine Increased risk of CNS depression Details Cetirizine Ophthalmic Thiopental Increased risk of CNS depression Details Cetirizine Ophthalmic Thiopropazate Increased risk of CNS depression Details Cetirizine Ophthalmic Thioridazine Increased risk of CNS depression Details Cetirizine Ophthalmic Tilidine Increased risk of CNS depression Details Cetirizine Ophthalmic Tizanidine Increased risk of CNS depression Details Cetirizine Ophthalmic Tolonium Chloride Increased risk of CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.