Cetirizine Ophthalmic

180 interactions 179 cited references

Also sold as: Zerviate Zerviate®

About Cetirizine Ophthalmic

Cetirizine ophthalmic is used to relieve the itching of allergic pink eye. Cetirizine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Read the full Cetirizine Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Isocarboxazid Zuranolone Secobarbital Scopolamine Ropeginterferon Alfa-2B-Njft Remoxipride

1 Contraindicated 175 Major 4 Moderate

All (180) Contraindicated (1) Major (175) Moderate (4)

Major

Cetirizine Ophthalmic Acepromazine PROMACE Increased risk of CNS depression Details Cetirizine Ophthalmic Alfentanil Increased risk of CNS depression Details Cetirizine Ophthalmic Alprazolam Xanax Increased risk of CNS depression Details Cetirizine Ophthalmic Amobarbital Amytal Increased risk of CNS depression Details Cetirizine Ophthalmic Anileridine Increased risk of CNS depression Details Cetirizine Ophthalmic Aripiprazole Abilify Increased risk of CNS depression Details Cetirizine Ophthalmic Asenapine Saphris Increased risk of CNS depression Details Cetirizine Ophthalmic Baclofen Fleqsuvy Increased risk of CNS depression Details Cetirizine Ophthalmic Benperidol Increased risk of CNS depression Details Cetirizine Ophthalmic Benzhydrocodone Increased risk of CNS depression Details Cetirizine Ophthalmic Bromazepam Increased risk of CNS depression Details Cetirizine Ophthalmic Buprenorphine Belbuca An increased risk of respiratory depression and CNS depression Details Cetirizine Ophthalmic Buspirone Bucapsol Increased risk of CNS depression Details Cetirizine Ophthalmic Butabarbital Increased risk of CNS depression Details Cetirizine Ophthalmic Butalbital An increased risk of CNS depression Details Cetirizine Ophthalmic Butorphanol Butorphic Increased risk of CNS depression Details Cetirizine Ophthalmic Calcium Oxybate Xywav An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Cetirizine Ophthalmic Cannabidiol Epidiolex Increased risk of CNS depression Details Cetirizine Ophthalmic Cannabis An increased risk of CNS depression Details Cetirizine Ophthalmic Carbamazepine Carbatrol An increased risk of CNS depression Details Cetirizine Ophthalmic Carbidopa Lodosyn An increased risk of CNS depression Details Cetirizine Ophthalmic Carbinoxamine Carbzah Increased risk of CNS depression Details Cetirizine Ophthalmic Carisoprodol Soma Increased risk of CNS depression Details Cetirizine Ophthalmic Carphenazine Increased risk of CNS depression Details Cetirizine Ophthalmic Chloral Hydrate Increased risk of CNS depression Details Cetirizine Ophthalmic Chlordiazepoxide Increased risk of CNS depression Details Cetirizine Ophthalmic Chlorpromazine Increased risk of CNS depression Details Cetirizine Ophthalmic Chlorzoxazone Lorzone Increased risk of CNS depression Details Cetirizine Ophthalmic Clobazam Onfi Increased risk of CNS depression Details Cetirizine Ophthalmic Clomipramine Anafranil An increased risk of CNS depression Details Cetirizine Ophthalmic Clonazepam Klonopin Increased risk of CNS depression Details Cetirizine Ophthalmic Clorazepate Tranxene Increased risk of CNS depression Details Cetirizine Ophthalmic Clozapine Clozaril Increased risk of CNS depression Details Cetirizine Ophthalmic Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Increased risk of CNS depression Details Cetirizine Ophthalmic Cyclobenzaprine Amrix Increased risk of CNS depression Details Cetirizine Ophthalmic Cyproheptadine An increased risk of CNS depression Details Cetirizine Ophthalmic Daridorexant An increased risk CNS depression Details Cetirizine Ophthalmic Dexmedetomidine Dexased Increased risk of CNS depression Details Cetirizine Ophthalmic Diacetylmorphine Increased risk of CNS depression Details Cetirizine Ophthalmic Diazepam Diastat Increased risk of CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.