Chloramphenicol

Name: Chloramphenicol Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

21 interactions 1 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Exenatide Injection Methotrexate Methotrexate Injection

3 Major 12 Moderate 6 Minor

All (21) Major (3) Moderate (12) Minor (6)

Minor

Chloramphenicol Acetaminophen And Codeine Capital® & Codeine Explained Chloramphenicol toxicity (vomiting, hypotension, hypothermia) Details Chloramphenicol Acetaminophen Acephen Chloramphenicol toxicity (vomiting, hypotension, hypothermia) Details Chloramphenicol Acetaminophen Injection Acephen Chloramphenicol toxicity (vomiting, hypotension, hypothermia) Details Chloramphenicol Acetaminophen Rectal Acephen Chloramphenicol toxicity (vomiting, hypotension, hypothermia) Details Chloramphenicol Penicillin G Procaine Injection Bactracillin G Decreased antibacterial effectiveness Details Chloramphenicol Penicillin V Potassium Beepen-VK® Decreased antibacterial effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.