Chlorprothixene

Name: Chlorprothixene Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

6 interactions 1 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Injection Metoclopramide Nasal Spray Cabergoline Hydroxychloroquine Lithium Carbonate

2 Contraindicated 3 Major 1 Moderate

All (6) Contraindicated (2) Major (3) Moderate (1)

Major

Chlorprothixene Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Chlorprothixene Hydroxychloroquine Plaquenil An increased risk of seizures Details Chlorprothixene Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.