Cimetidine
83 interactions 6 explained in plain English
Also sold as:
Tagamet
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Dofetilide
Colchicine
Meloxicam Injection
Infigratinib
Fluorouracil Injection
Octreotide Injection
Major
Cimetidine Metronidazole Injection Flagyl Increased metroNIDAZOLE exposure Details Cimetidine Metronidazole Topical MetroCream® Increased metroNIDAZOLE exposure Details Cimetidine Metronidazole Vaginal MetroGel® Vaginal Increased metroNIDAZOLE exposure Details Cimetidine Morphine Injection Astramorph® PF Increased risk of apnea, confusion and muscle twitching, an increased morphine exposure and an increased risk of morphine toxicity... Details Cimetidine Neratinib Nerlynx Decreased neratinib solubility, absorption, and exposure Details Cimetidine Nifedipine Adalat® Increased NIFEdipine exposure and an increased risk of NIFEdipine-related adverse reactions (headache, peripheral edema, hypotensi... Details Cimetidine Octreotide Bynfezia Decreased octreotide bioavailability Details Cimetidine Octreotide Injection Bynfezia Decreased octreotide bioavailability DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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