Cladribine Injection

Name: Cladribine Injection Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

16 interactions 157 cited references

Also sold as: Leustatin® Mavenclad

About Cladribine Injection

Cladribine is used to treat hairy cell leukemia (cancer of a certain type of white blood cell). Cladribine is in a class of medications known as purine analogs. It works by stopping or slowing the growth of cancer cells. Read the full Cladribine Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live

9 Contraindicated 7 Major

All (16) Contraindicated (9) Major (7)

Major

Cladribine Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Cladribine Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Cladribine Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Cladribine Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Cladribine Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Cladribine Injection Islatravir Reduced islatravir-triphosphate exposure and reduced efficacy of islatravir Details Cladribine Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.