Clobetasol

32 interactions 229 cited references
Also sold as: Byqlovi Clobex Clodan Impeklo Impoyz Olux Temovate Tovet

Read the full Clobetasol drug information page

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Desmopressin Desmopressin Nasal Aspirin Bemiparin Carbamazepine
3 Contraindicated 19 Major 10 Moderate
All (32) Contraindicated (3) Major (19) Moderate (10)

Major

Clobetasol Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Clobetasol Aspirin Rectal Aspirin An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Clobetasol Bemiparin Increased risk of bleeding Details Clobetasol Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Clobetasol Cosyntropin False elevations of plasma cortisol levels Details Clobetasol Ethinyl Estradiol Increased corticosteroid exposure Details Clobetasol Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Clobetasol Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Clobetasol Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Clobetasol Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Clobetasol Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Clobetasol Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Clobetasol Nadroparin Increased risk of bleeding Details Clobetasol Phenytoin Dilantin Reduced corticosteroid exposure Details Clobetasol Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Clobetasol Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Clobetasol Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Clobetasol Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Clobetasol Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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