Deucravacitinib

18 interactions 11 cited references
Also sold as: Sotyktu Sotyktu®
About Deucravacitinib

Deucravacitinib is used to treat moderate to severe plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in adults 18 years of age or older whose psoriasis is too severe to be treated by topical medications alone. Deucravacitinib should not be taken with other medications that su… Read the full Deucravacitinib drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine, Live Poliovirus Vaccine, Live Rotavirus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Yellow Fever Vaccine
17 Major 1 Moderate
All (18) Major (17) Moderate (1)

Moderate

Deucravacitinib Levothyroxine Ermeza Increased risk of hypothyroidism Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.