Dexibuprofen

87 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Ophthalmic Ketorolac Ketorolac Nasal Spray Ketorolac Injection Furosemide Injection Pemetrexed Injection
4 Contraindicated 55 Major 28 Moderate
All (87) Contraindicated (4) Major (55) Moderate (28)

Moderate

Dexibuprofen Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Atenolol Tenormin Explained Reduced antihypertensive effect Details Dexibuprofen Acebutolol Sectral® Reduced antihypertensive effect Details Dexibuprofen Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Betaxolol Betoptic S Reduced antihypertensive effect Details Dexibuprofen Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Dexibuprofen Bisoprolol Zebeta® Reduced antihypertensive effect Details Dexibuprofen Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Dexibuprofen Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Esmolol Brevibloc Reduced antihypertensive effect Details Dexibuprofen Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Labetalol Normodyne® Reduced antihypertensive effect Details Dexibuprofen Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Dexibuprofen Levofloxacin Levaquin An increased risk of seizures Details Dexibuprofen Levofloxacin Injection Levaquin An increased risk of seizures Details Dexibuprofen Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Dexibuprofen Nadolol Corgard Reduced antihypertensive effect Details Dexibuprofen Nebivolol Bystolic Reduced antihypertensive effect Details Dexibuprofen Ofloxacin Floxin® An increased risk of seizures Details Dexibuprofen Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Dexibuprofen Ofloxacin Otic Floxin® Otic An increased risk of seizures Details Dexibuprofen Penbutolol Levatol® Reduced antihypertensive effect Details Dexibuprofen Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.