Dolasetron

332 interactions 1 explained in plain English 421 cited references
Also sold as: Anzemet Anzemet®
About Dolasetron

Dolasetron is used to prevent nausea and vomiting caused by cancer chemotherapy. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Read the full Dolasetron drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Piperaquine Phenelzine Saquinavir Pimozide Mesoridazine Sparfloxacin
16 Contraindicated 314 Major 1 Moderate 1 Minor
All (332) Contraindicated (16) Major (314) Moderate (1) Minor (1)

Major

Dolasetron Azimilide Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Benzhydrocodone An increased risk of serotonin syndrome Details Dolasetron Benzphetamine An increased risk of serotonin syndrome Details Dolasetron Bretylium Cardiotoxicity (QT prolongation, torsade de pointes, cardiac arrest) Details Dolasetron Brompheniramine Respa-BR Increased risk of serotonin syndrome Details Dolasetron Buspirone Bucapsol Increased risk of serotonin syndrome Details Dolasetron Butorphanol Butorphic Increased risk of serotonin syndrome Details Dolasetron Carbamazepine Carbatrol Increased risk of serotonin syndrome Details Dolasetron Ceritinib Zykadia An increased risk of QT interval prolongation Details Dolasetron Chloral Hydrate An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Chlorpheniramine Increased risk of serotonin syndrome Details Dolasetron Chlorpromazine Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Dolasetron Ciprofloxacin An increased risk of QT interval prolongation and torsade de pointes Details Dolasetron Citalopram Celexa Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Clarithromycin Biaxin Increased risk of QT interval prolongation Details Dolasetron Clofazimine An increased risk of QT interval prolongation Details Dolasetron Clomipramine Anafranil Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Clothiapine Increased risk of cardiac arrhythmias Details Dolasetron Clozapine Clozaril Increased risk of QT interval prolongation Details Dolasetron Cocaine Goprelto Increased risk of serotonin syndrome Details Dolasetron Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Increased risk of serotonin syndrome Details Dolasetron Crizotinib Xalkori An increased risk of QT interval prolongation Details Dolasetron Cyclobenzaprine Amrix Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Dabrafenib Tafinlar An increased risk of QT interval prolongation Details Dolasetron Degarelix Firmagon Increased risk of QT interval prolongation Details Dolasetron Delamanid Increased risk of QT interval prolongation Details Dolasetron Desflurane Suprane An increased risk of QT interval prolongation Details Dolasetron Desipramine Norpramin Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Desvenlafaxine Pristiq Increased risk of serotonin syndrome Details Dolasetron Dexmedetomidine Dexased Increased risk of cardiac arrhythmias Details Dolasetron Dextroamphetamine Dexedrine An increased risk of serotonin syndrome Details Dolasetron Dextromethorphan Delsym Increased risk of serotonin syndrome Details Dolasetron Dibenzepin Increased risk of serotonin syndrome Details Dolasetron Dihydrocodeine Increased risk of serotonin syndrome Details Dolasetron Domperidone Increased risk of QT interval prolongation Details Dolasetron Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Dolasetron Dordaviprone An increased risk of QT interval prolongation Details Dolasetron Doxepin Prudoxin Increased risk of serotonin syndrome and QT-interval prolongation Details Dolasetron Droperidol An increased risk of QT interval prolongation Details Dolasetron Duloxetine Increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.