Doxorubicin Hydrochloride Liposome
40 interactions 3 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Amitriptyline
Cyclophosphamide Injection
Cyclosporine Ophthalmic
Dexamethasone Ophthalmic
Clotrimazole
Clotrimazole Lozenge
Major
Doxorubicin Hydrochloride Liposome Amitriptyline Elavil Explained Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Sertraline Explained Increased CYP2D6 substrate exposure Details Doxorubicin Hydrochloride Liposome Abrocitinib Cibinqo Explained Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Azathioprine Azasan An increased risk of hepatotoxicity Details Doxorubicin Hydrochloride Liposome Azithromycin AzaSite Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Atorvastatin Atorvaliq Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Abiraterone Abirtega Increased DOXOrubicin exposure Details Doxorubicin Hydrochloride Liposome Alogliptin Nesina Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Canagliflozin Invokana Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Capmatinib Tabrecta Increased P-gp substrate exposure and an increased risk of increased adverse reactions Details Doxorubicin Hydrochloride Liposome Captopril Capoten® Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Cisplatin Injection Platinol-AQ® Leukemia Details Doxorubicin Hydrochloride Liposome Clotrimazole Aardora Anti-Fungal Maximum Strength Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Clotrimazole Lozenge Mycelex® Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Clotrimazole Topical Cruex Antifungal Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Clotrimazole Vaginal Gyne-Lotrimin 3® Cream Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Cyclophosphamide Cytoxan® Increased risk of cardiomyopathy Details Doxorubicin Hydrochloride Liposome Cyclophosphamide Injection Cytoxan® Injection Increased risk of cardiomyopathy Details Doxorubicin Hydrochloride Liposome Cyclosporine Injection Atopica Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Cyclosporine Ophthalmic Cequa Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Dexamethasone Injection Decadron Reduced DOXOrubicin exposure Details Doxorubicin Hydrochloride Liposome Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced DOXOrubicin exposure Details Doxorubicin Hydrochloride Liposome Elacestrant Orserdu Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Enasidenib Idhifa Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Entrectinib Rozlytrek Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Felodipine Plendil® Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Fostamatinib Tavalisse Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Ibrexafungerp Brexafemme Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Istradefylline Nourianz Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Ketoconazole Topical Extina® Foam Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Lenacapavir Injection Sunlenca Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Lenacapavir Oral Sunlenca Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Letermovir Injection Prevymis Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Doxorubicin Hydrochloride Liposome Nafcillin Injection Unipen® Injection Reduced DOXOrubicin exposure Details Doxorubicin Hydrochloride Liposome Neratinib Nerlynx Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Doxorubicin Hydrochloride Liposome Nevirapine Viramune Reduced DOXOrubicin exposure Details Doxorubicin Hydrochloride Liposome Nifedipine Adalat® Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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