Dronedarone

146 interactions 12 explained in plain English
Also sold as: Multaq
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Galantamine Octreotide Injection Cyclosporine Ophthalmic Relugolix Ofloxacin Otic Foscarnet Injection
66 Contraindicated 73 Major 7 Moderate
All (146) Contraindicated (66) Major (73) Moderate (7)

Contraindicated

Dronedarone Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Dronedarone Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Dronedarone Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Dronedarone Ivabradine Corlanor Increased risk of QT interval prolongation Details Dronedarone Ketoconazole Topical Extina® Foam Increased dronedarone exposure and an increased risk of QT interval prolongation Details Dronedarone Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions, an increased dronedarone exposure, an incr... Details Dronedarone Lenvatinib Lenvima Increased risk of QT interval prolongation Details Dronedarone Levofloxacin Levaquin Increased risk of QT interval prolongation Details Dronedarone Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Dronedarone Loperamide Diamode Increased loperamide exposure, an increased risk of loperamide-related adverse effects and an increased risk of QT interval prolon... Details Dronedarone Mefloquine Lariam® Increased risk of QT interval prolongation Details Dronedarone Metronidazole Flagyl Increased risk of QT interval prolongation Details Dronedarone Metronidazole Injection Flagyl Increased risk of QT interval prolongation Details Dronedarone Metronidazole Topical MetroCream® Increased risk of QT interval prolongation Details Dronedarone Metronidazole Vaginal MetroGel® Vaginal Increased risk of QT interval prolongation Details Dronedarone Moxifloxacin Avelox Increased risk of QT interval prolongation Details Dronedarone Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Dronedarone Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Dronedarone Nafarelin Nasal Spray Synarel Increased risk of QT interval prolongation Details Dronedarone Octreotide Bynfezia Increased risk of QT interval prolongation Details Dronedarone Octreotide Injection Bynfezia Increased risk of QT interval prolongation Details Dronedarone Ofloxacin Floxin® Increased risk of QT interval prolongation Details Dronedarone Ofloxacin Ophthalmic Ocuflox Increased risk of QT interval prolongation Details Dronedarone Ofloxacin Otic Floxin® Otic Increased risk of QT interval prolongation Details Dronedarone Olodaterol Oral Inhalation Striverdi Increased risk of QT interval prolongation Details Dronedarone Oxaliplatin Injection Eloxatin® Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.