Droperidol

91 interactions 4 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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86 Major 5 Moderate

All (91) Major (86) Moderate (5)

Major

Droperidol Fostemsavir Rukobia Increased risk of torsade de pointes Details Droperidol Galantamine Razadyne An increased risk of QT interval prolongation Details Droperidol Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Droperidol Gemifloxacin Factive An increased risk of QT interval prolongation Details Droperidol Glasdegib Daurismo Increased risk of QT interval prolongation Details Droperidol Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Droperidol Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details Droperidol Granisetron Injection Granisol An increased risk of QT interval prolongation Details Droperidol Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Droperidol Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Droperidol Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Droperidol Hydroxychloroquine Plaquenil An increased risk of seizures and an increased risk of QT interval prolongation Details Droperidol Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Droperidol Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Droperidol Ivabradine Corlanor Increased risk of QT prolongation Details Droperidol Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Droperidol Lacosamide Injection Motpoly An increased risk of CNS depression Details Droperidol Lefamulin Xenleta Increased risk of QT interval prolongation Details Droperidol Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Droperidol Levodopa Oral Inhalation Inbrija Reduce efficacy of levodopa (foslevodopa), an increased risk of exacerbating psychosis [or symptoms of Parkinson's disease: delusi... Details Droperidol Levofloxacin Levaquin Increased risk of QT interval prolongation Details Droperidol Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Droperidol Linezolid Injection Zyvox An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Droperidol Lithium Carbonate Lithobid Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Details Droperidol Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Droperidol Mefloquine Lariam® An increased risk of QT interval prolongation Details Droperidol Metoclopramide Injection Gimoti Increased risk of CNS depression Details Droperidol Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Droperidol Metronidazole Flagyl An increased risk of QT interval prolongation Details Droperidol Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Droperidol Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Droperidol Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Droperidol Midazolam Nasal Spray Nayzilam An increased risk of CNS depression Details Droperidol Midazolam Injection Nayzilam An increased risk of CNS depression Details Droperidol Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Droperidol Moxifloxacin Avelox Increased risk of QT interval prolongation Details Droperidol Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Droperidol Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Droperidol Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Droperidol Octreotide Bynfezia An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.