Droperidol

91 interactions 4 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Foscarnet Injection Galantamine Ofloxacin Otic Relugolix Oxaliplatin Injection Octreotide Injection

86 Major 5 Moderate

All (91) Major (86) Moderate (5)

Major

Droperidol Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Droperidol Sertraline Explained An increased risk of QT interval prolongation Details Droperidol Buprenorphine Belbuca Explained An increased risk of QT interval prolongation and an increased risk of CNS and respiratory depression Details Droperidol Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Droperidol Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Droperidol Arsenic Trioxide Trisenox An increased risk of QT interval prolongation, and an increased risk of torsades de pointes Details Droperidol Aripiprazole Injection Abilify An increased risk of QT interval prolongation and an increased risk of CNS depression Details Droperidol Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation, and an increased risk of torsades de pointes Details Droperidol Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation and an increased risk of CNS depression Details Droperidol Azithromycin AzaSite An increased risk of QT interval prolongation Details Droperidol Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Droperidol Alfuzosin UroXatral An increased risk of QT interval prolongation Details Droperidol Anagrelide Agrylin Increased risk of QT interval prolongation Details Droperidol Bedaquiline Sirturo Increased risk of QT interval prolongation Details Droperidol Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Droperidol Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Droperidol Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Droperidol Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Droperidol Chloroquine Aralen® An increased risk of QT interval prolongation Details Droperidol Dasatinib Phyrago An increased risk of QT interval prolongation Details Droperidol Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Droperidol Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Droperidol Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Droperidol Diazepam Rectal Diastat Increased risk of CNS depression Details Droperidol Diphenhydramine Injection Banophen An increased risk of CNS depression Details Droperidol Diphenhydramine Topical Afterbite with Antihistamine An increased risk of CNS depression Details Droperidol Disopyramide Norpace An increased risk of QT interval prolongation Details Droperidol Dofetilide Tikosyn An increased risk of QT interval prolongation Details Droperidol Dolasetron Anzemet An increased risk of QT interval prolongation Details Droperidol Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Droperidol Encorafenib Braftovi Increased risk of QT interval prolongation Details Droperidol Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Droperidol Eribulin Injection Halaven An increased risk of QT interval prolongation Details Droperidol Esketamine Nasal Spray Spravato Increased risk of sedation Details Droperidol Famotidine Calmicid An increased risk of QT interval prolongation Details Droperidol Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Droperidol Felbamate Felbatol An increased risk of QT interval prolongation Details Droperidol Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Droperidol Flecainide Tambocor® An increased risk of QT interval prolongation Details Droperidol Foscarnet Injection Foscavir An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.