Efavirenz
137 interactions 8 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Maraviroc
Atovaquone
Dabigatran Etexilate
Ifosfamide Injection
Azithromycin
Orlistat
Moderate
Efavirenz Simvastatin Flolipid Explained Reduced simvastatin exposure Details Efavirenz Atorvastatin Atorvaliq Reduced atorvastatin exposure Details Efavirenz Amlodipine Amvaz® Reduced calcium channel blocker exposure Details Efavirenz Caspofungin Injection Cancidas Reduced caspofungin plasma levels Details Efavirenz Clopidogrel Plavix Altered clopidogrel active metabolite exposure and altered platelet inhibition and an increased risk of bleeding Details Efavirenz Felodipine Plendil® Reduced calcium channel blocker exposure Details Efavirenz Guanfacine Intuniv Decreased guanfacine exposure Details Efavirenz Hydrocortisone Ala-Cort Reduced hydrocortisone exposure Details Efavirenz Hydrocortisone Injection A-Hydrocort® Reduced hydrocortisone exposure Details Efavirenz Isradipine DynaCirc® Reduced calcium channel blocker exposure Details Efavirenz Nicardipine Cardene Reduced calcium channel blocker exposure Details Efavirenz Nimodipine Nimotop Reduced calcium channel blocker exposure Details Efavirenz Nisoldipine Sular Reduced calcium channel blocker exposure Details Efavirenz Ospemifene Osphena Decreased ospemifene exposure and efficacy DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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