Enoxaparin and Asafetida: Interaction Details
AI-assisted, pharmacist-reviewed · Source data updated Aug 8, 2026 · Sources: FDA labeling, DDInter 2.0, cited literature
Enoxaparin
Asafetida
No brand names on recordHow we grade severity & evidence
Severity levels
- Contraindicated: These should generally not be used together.
- Major: Potentially serious — often needs a change or close monitoring.
- Moderate: Can be significant — usually manageable with monitoring.
- Minor: Usually limited clinical impact.
Evidence grades
- Established: Well documented — supported by controlled studies or strong clinical data.
- Probable: Good supporting evidence, though not definitively proven.
- Suspected: Some evidence suggests this interaction, but it is not well established.
- Possible: Limited or conflicting evidence; the interaction may occur.
- Theoretical: Predicted from the drugs' pharmacology; not yet confirmed in people.
Ratings come from the documented interaction literature and are reviewed by a pharmacist. They describe the documented risk of the combination, not what will necessarily happen to you — your dose, timing, and health picture all matter.
What happens
Increased risk of bleeding
Interaction Deep Dive
Theoretically, asafetida may potentiate the effects of low molecular weight heparins2. Asafetida contains free ferulic acid, coumarin derivatives, and coumarin sesquiterpene complexes. Asafoetida has been reported to have anticoagulant effects in animals 1. Caution is advised.
Why it happens (mechanism)
Additive anticoagulant effects
Common questions
Can I take Enoxaparin and Asafetida together?
Increased risk of bleeding Always confirm with your pharmacist or prescriber before making any change.
How serious is the Enoxaparin and Asafetida interaction?
It is rated moderate. Can be significant — usually manageable with monitoring.
How quickly could this interaction happen?
The documented onset is "delayed". Effects tend to build up gradually over days to weeks.
How strong is the evidence for this interaction?
The evidence is graded "theoretical". Predicted from the drugs' pharmacology; not yet confirmed in people.
From our Q&A
Real reader questions about these medications, each personally answered by our pharmacist:
Questions for your pharmacist
- Does my dose of Enoxaparin or Asafetida need adjusting while I take them together?
- What symptoms should prompt me to call you or my prescriber right away?
- Does the timing of my doses matter for this combination?
- Is there anything you'd monitor while I'm on both?
References (2)
- Newall CA, Anderson LA, & Phillipson JDNewall CA, Anderson LA, & Phillipson JD: Herbal Medicines: A Guide for Healthcare Professionals, The Pharmaceutical Press, London, England, 1996.
- Heck AM, DeWitt BA, & Lukes AL: Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000; 57(13):1221-1227. DOI
Keep reading about Enoxaparin
These medications also interact with supplements
Prescription drugs aren't the whole picture — herbal and dietary supplements can interact with them too. From the evidence-graded Natural Medicines database:
major · moderate · minor — check everything you take with our drug–supplement interaction checker.
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