Estradiol

Major

Estradiol Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Estradiol Itraconazole Sporanox Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects Details Estradiol Ivosidenib Tibsovo Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of breakthrough bleeding a... Details Estradiol Lemborexant Dayvigo Increased lemborexant exposure and an increased risk of lemborexant-related adverse reactions. Details Estradiol Lesinurad Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive and increased risk of breakthrough bleeding an... Details Estradiol Letermovir Prevymis Increased CYP3A substrate exposure Details Estradiol Lisdexamfetamine Arynta Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Estradiol Lixisenatide Decreased absorption of oral contraceptives Details Estradiol Lomitapide Increased lomitapide exposure Details Estradiol Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Estradiol Lorlatinib Lorbrena Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of breakthrough bleeding a... Details Estradiol Lumacaftor Decreased hormonal contraceptive exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Estradiol Mavacamten Camzyos Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive, increased mavacamten exposure and an increase... Details Estradiol Melatonin Increased melatonin exposure Details Estradiol Meropenem Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Estradiol Methylergonovine Methergine Increased methylergonovine exposure Details Estradiol Mifepristone Korlym Reduced hormonal contraceptive exposure, an increased miFEPRIStone exposure and an increased hormonal contraceptives exposure Details Estradiol Minocycline Amzeeq Decreased contraceptive efficacy Details Estradiol Mitapivat Aqvesme Reduced hormonal contraceptive exposure Details Estradiol Mitotane Lysodren Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive and increased risk of breakthrough bleeding an... Details Estradiol Mobocertinib Exkivity Reduced exposure of the hormonal contraceptive, which may result in reduced contraceptive efficacy and an increased risk of breakt... Details Estradiol Modafinil Provigil Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of breakthrough bleeding a... Details Estradiol Mycophenolate Mofetil Reduced levonorgestrel exposure and reduced efficacy of combination oral contraceptive Details Estradiol Mycophenolic Acid Myfortic Decreased contraceptive efficacy Details Estradiol Nafcillin Reduced hormonal contraceptive exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Estradiol Nelfinavir Viracept Increased nelfinavir exposure, reduced estrogen/progestin exposure and contraceptive failure Details Estradiol Netupitant Increased exposure of CYP3A4 substrate Details Estradiol Nevirapine Viramune Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of breakthrough bleeding a... Details Estradiol Nifedipine Adalat® Increased NIFEdipine exposure Details Estradiol Octreotide Bynfezia Decreased bioavailability and decreased efficacy of combined oral contraceptives or increased breakthrough bleeding Details Estradiol Omaveloxolone Skyclarys Reduced hormonal contraceptive exposure, reduced efficacy of contraceptive and an increased risk of breakthrough bleeding/contrace... Details Estradiol Orforglipron Foundayo Reduced oral contraceptives absorption and reduced efficacy of oral contraceptives Details Estradiol Oxacillin Decreased contraceptive effectiveness Details Estradiol Oxcarbazepine Oxtellar Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of contraceptive failure Details Estradiol Oxytetracycline Decreased contraceptive effectiveness Details Estradiol Pacritinib Vonjo® Reduced efficacy of hormonal contraceptives Details Estradiol Penicillin G Decreased contraceptive effectiveness Details Estradiol Penicillin G Procaine Decreased contraceptive effectiveness Details Estradiol Penicillin V Decreased contraceptive effectiveness Details Estradiol Phenobarbital Fidoquel Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive and an increased risk of breakthrough bleeding... Details