Flurbiprofen

299 interactions 378 cited references

Also sold as: Ansaid Ansaid® Lurbipr Lurbiro Ocufen

About Flurbiprofen

Flurbiprofen is an NSAID used to relieve pain, swelling, and stiffness from osteoarthritis and rheumatoid arthritis. Read the full Flurbiprofen drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Injection Ketorolac Ketorolac Ophthalmic Ketorolac Nasal Spray Escitalopram Pemetrexed Injection

4 Contraindicated 235 Major 60 Moderate

All (299) Contraindicated (4) Major (235) Moderate (60)

Major

Flurbiprofen Acenocoumarol An increased risk of bleeding Details Flurbiprofen Amiloride Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Flurbiprofen Amineptine An increased risk of bleeding Details Flurbiprofen Amitriptylinoxide An increased risk of bleeding Details Flurbiprofen Amoxapine An increased risk of bleeding Details Flurbiprofen Amtolmetin Guacil Increased risk of bleeding Details Flurbiprofen Apalutamide Erleada Reduced CYP2C9 substrates exposure Details Flurbiprofen Ardeparin An increased risk of bleeding Details Flurbiprofen Argatroban An increased risk of bleeding Details Flurbiprofen Balsalazide Colazal Increased risk of bleeding Details Flurbiprofen Bemetizide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Bemiparin An increased risk of bleeding Details Flurbiprofen Bendroflumethiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Benzthiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Bismuth Subsalicylate Bismarex Increased risk of bleeding Details Flurbiprofen Bivalirudin Angiomax An increased risk of bleeding Details Flurbiprofen Bromfenac Bromsite Increased risk of bleeding Details Flurbiprofen Bufexamac Increased risk of bleeding Details Flurbiprofen Bumetanide Bumex Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Cangrelor Kengreal An increased risk of bleeding Details Flurbiprofen Carbamazepine Carbatrol Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details Flurbiprofen Celecoxib Celebrex An increased risk of GI toxicity and an increased risk of bleeding Details Flurbiprofen Certoparin An increased risk of bleeding Details Flurbiprofen Chlorothiazide Diuril Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Chlorthalidone Hemiclor Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Choline Magnesium Trisalicylate Trilisate® Increased risk of bleeding Details Flurbiprofen Choline Salicylate Increased risk of bleeding Details Flurbiprofen Cilostazol Pletal® An increased risk of bleeding Details Flurbiprofen Citalopram Celexa An increased risk of bleeding Details Flurbiprofen Clomipramine Anafranil An increased risk of bleeding Details Flurbiprofen Clonixin Increased risk of bleeding Details Flurbiprofen Clopamide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Cyclopenthiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Cyclosporine Atopica An increased risk of cycloSPORINE nephrotoxicity Details Flurbiprofen Cyclothiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Dalteparin Fragmin An increased risk of bleeding Details Flurbiprofen Danaparoid An increased risk of bleeding Details Flurbiprofen Desipramine Norpramin An increased risk of bleeding Details Flurbiprofen Desirudin Iprivask An increased risk of bleeding Details Flurbiprofen Desvenlafaxine Pristiq An increased risk of bleeding Details

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