Flurbiprofen

299 interactions 378 cited references
Also sold as: Ansaid Ansaid® Lurbipr Lurbiro Ocufen
About Flurbiprofen

Flurbiprofen is an NSAID used to relieve pain, swelling, and stiffness from osteoarthritis and rheumatoid arthritis. Read the full Flurbiprofen drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Injection Ketorolac Ketorolac Ophthalmic Ketorolac Nasal Spray Escitalopram Pemetrexed Injection
4 Contraindicated 235 Major 60 Moderate
All (299) Contraindicated (4) Major (235) Moderate (60)

Moderate

Flurbiprofen Ofloxacin Floxin® An increased risk of seizures Details Flurbiprofen Olmesartan Benicar Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Oxprenolol Reduced antihypertensive effect Details Flurbiprofen Penbutolol Levatol® Reduced antihypertensive effect Details Flurbiprofen Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Pindolol Visken® Reduced antihypertensive effect Details Flurbiprofen Pralatrexate Increased pralatrexate exposure Details Flurbiprofen Propranolol Hemangeol Reduced antihypertensive effect Details Flurbiprofen Quinapril Accupril Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Ramipril Altace Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Sotalol Betapace Reduced antihypertensive effect Details Flurbiprofen Spirapril Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Telmisartan Micardis Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Timolol Betimol Reduced antihypertensive effect Details Flurbiprofen Trandolapril Mavik® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Valsartan Diovan Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Flurbiprofen Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Flurbiprofen Levofloxacin Injection Levaquin An increased risk of seizures Details Flurbiprofen Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Flurbiprofen Ofloxacin Otic Floxin® Otic An increased risk of seizures Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.