Flurbiprofen

299 interactions 378 cited references
Also sold as: Ansaid Ansaid® Lurbipr Lurbiro Ocufen
About Flurbiprofen

Flurbiprofen is an NSAID used to relieve pain, swelling, and stiffness from osteoarthritis and rheumatoid arthritis. Read the full Flurbiprofen drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Flurbiprofen Tenoxicam Increased risk of bleeding Details Flurbiprofen Tianeptine An increased risk of bleeding Details Flurbiprofen Tiaprofenic Acid Increased risk of bleeding Details Flurbiprofen Ticagrelor Brilinta An increased risk of bleeding Details Flurbiprofen Ticlopidine Ticlid® An increased risk of bleeding Details Flurbiprofen Tinzaparin An increased risk of bleeding Details Flurbiprofen Tirofiban An increased risk of bleeding Details Flurbiprofen Tolfenamic Acid Increased risk of bleeding Details Flurbiprofen Tolmetin Tolectin 600 Increased risk of bleeding Details Flurbiprofen Torsemide Soaanz Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Trazodone Raldesy An increased risk of bleeding Details Flurbiprofen Treprostinil Orenitram An increased risk of bleeding Details Flurbiprofen Triamterene Dyrenium Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Flurbiprofen Trichlormethiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Trimipramine An increased risk of bleeding Details Flurbiprofen Trolamine Salicylate Increased risk of bleeding Details Flurbiprofen Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details Flurbiprofen Valdecoxib Increased risk of bleeding Details Flurbiprofen Venlafaxine An increased risk of bleeding Details Flurbiprofen Vilazodone Viibryd An increased risk of bleeding Details Flurbiprofen Vorapaxar Zontivity An increased risk of bleeding Details Flurbiprofen Voriconazole Vfend Increased NSAIDs exposure Details Flurbiprofen Vortioxetine Trintellix An increased risk of bleeding Details Flurbiprofen Warfarin Coumadin An increased risk of bleeding Details Flurbiprofen Xipamide Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Fondaparinux Injection Arixtra An increased risk of bleeding Details Flurbiprofen Furosemide Injection Disal Reduced diuretic effectiveness and possible nephrotoxicity Details Flurbiprofen Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Flurbiprofen Hydrocortisone Injection A-Hydrocort® Increased risk of gastrointestinal ulcer or bleeding Details Flurbiprofen Lithium Carbonate Lithobid Increased lithium exposure and an increased risk of lithium toxicity Details Flurbiprofen Meloxicam Injection Alloxate Increased risk of bleeding Details Flurbiprofen Melphalan Injection Alkeran An increased risk of bleeding Details Flurbiprofen Mesalamine Rectal Canasa Increased risk of bleeding Details Flurbiprofen Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Flurbiprofen Pemetrexed Injection Alimta Increased PEMEtrexed exposure and an increased risk of PEMEtrexed toxicity (myelosuppression, renal toxicity, and gastrointestinal... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.