Folic Acid

94 interactions 132 cited references

Also sold as: Folacin Folicet® Folvite® Quiofic

About Folic Acid

A B-vitamin used to treat or prevent folic acid deficiency and certain types of anemia caused by low red blood cell count. Read the full Folic Acid drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Capecitabine Pafolacianine Fluorouracil Injection Methotrexate Injection Doxifluridine Fosphenytoin

14 Major 79 Moderate 1 Minor

All (94) Major (14) Moderate (79) Minor (1)

Moderate

Folic Acid Acetazolamide Diamox® Sequels® Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Brivaracetam Briviact Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Brivaracetam Injection Briviact Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cholestyramine Resin Locholest® Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Colestipol Colestid Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Diazepam Nasal Spray Valtoco Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Diazepam Rectal Diastat Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Ethosuximide Zarontin Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Famotidine Calmicid Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Famotidine Injection Calmicid Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Felbamate Felbatol Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Aluminum Carbonate, Basic Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Aluminum Hydroxide AlternaGEL® Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Aluminum Phosphate Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Amobarbital Amytal Reduced folic acid exposure, reduced barbiturates exposure and reduced efficacy of barbiturate Details Folic Acid Barbital Reduced folic acid exposure, reduced barbiturates exposure and reduced efficacy of barbiturate Details Folic Acid Butabarbital Reduced folic acid exposure, reduced barbiturates exposure and reduced efficacy of barbiturate Details Folic Acid Calcium Carbonate Alka-Mints Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Calcium Silicate Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cannabidiol Epidiolex Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Carbamazepine Carbatrol Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cenobamate Xcopri Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cholestyramine Prevalite Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cimetidine Tagamet Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Clobazam Onfi Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Clonazepam Klonopin Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Clorazepate Tranxene Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Cycloserine Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Diazepam Diastat Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Dihydroxyaluminum Aminoacetate Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Dihydroxyaluminum Sodium Carbonate Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Ebrotidine Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Eslicarbazepine Acetate Aptiom Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Gabapentin Gabarone Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Ganaxolone Ztalmy Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Hexobarbital Reduced folic acid exposure, reduced barbiturates exposure and reduced efficacy of barbiturate Details Folic Acid Isoniazid Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Lacosamide Motpoly Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Lamotrigine Lamictal Reduced folic acid exposure and reduced efficacy of folic acid Details Folic Acid Levetiracetam Elepsia Reduced folic acid exposure and reduced efficacy of folic acid Details

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