Fosinopril

193 interactions 566 cited references
Also sold as: Monopril®
About Fosinopril

Fosinopril is an ACE inhibitor used to treat high blood pressure and heart failure. Read the full Fosinopril drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Fosinopril Clonixin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Clopamide Reduction of blood pressure Details Fosinopril Cyclopenthiazide Reduction of blood pressure Details Fosinopril Cyclothiazide Reduction of blood pressure Details Fosinopril Dexibuprofen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Dexketoprofen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Diclofenac Aleve Arthritis Pain Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Diflunisal Dolobid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Dipyrone Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Droxicam Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Dulaglutide Trulicity An increased risk of hypoglycemia Details Fosinopril Ethacrynic Acid Edecrin Postural hypotension (first dose) Details Fosinopril Etofenamate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Etoricoxib Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Etozolin Postural hypotension (first dose) Details Fosinopril Exenatide Bydureon An increased risk of hypoglycemia Details Fosinopril Felbinac Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Fepradinol Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Feprazone Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Floctafenine Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Flufenamic Acid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Glimepiride Amaryl An increased risk of hypoglycemia Details Fosinopril Glipizide Glucotrol An increased risk of hypoglycemia Details Fosinopril Glyburide DiaBeta® An increased risk of hypoglycemia Details Fosinopril Gold Sodium Thiomalate Nitritoid reactions (facial flushing, nausea, vomiting, and hypotension) Details Fosinopril Hydrochlorothiazide Inzirqo Reduction of blood pressure Details Fosinopril Hydroflumethiazide Reduction of blood pressure Details Fosinopril Ibuprofen Addaprin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Icatibant Firazyr Reduced fosinopril effectiveness Details Fosinopril Indapamide Reduction of blood pressure Details Fosinopril Indomethacin Indocin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Insulin Afrezza An increased risk of hypoglycemia Details Fosinopril Insulin Aspart, Recombinant Fiasp An increased risk of hypoglycemia Details Fosinopril Insulin Bovine An increased risk of hypoglycemia Details Fosinopril Insulin Degludec Tresiba An increased risk of hypoglycemia Details Fosinopril Insulin Detemir Levemir An increased risk of hypoglycemia Details Fosinopril Insulin Glargine, Recombinant Basaglar An increased risk of hypoglycemia Details Fosinopril Insulin Glulisine Apidra An increased risk of hypoglycemia Details Fosinopril Insulin Lispro, Recombinant Admelog An increased risk of hypoglycemia Details Fosinopril Ketoprofen Actron® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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