Fosinopril

193 interactions 566 cited references

Also sold as: Monopril®

About Fosinopril

Fosinopril is an ACE inhibitor used to treat high blood pressure and heart failure. Read the full Fosinopril drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aliskiren Valsartan Sacubitril Furosemide Eplerenone Lithium Carbonate

3 Contraindicated 38 Major 152 Moderate

All (193) Contraindicated (3) Major (38) Moderate (152)

Moderate

Fosinopril Quinethazone Reduction of blood pressure Details Fosinopril Repaglinide Prandin® An increased risk of hypoglycemia Details Fosinopril Rofecoxib Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Rosiglitazone Avandia® An increased risk of hypoglycemia Details Fosinopril Salicylic Acid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Salsalate Disalcid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Saxagliptin Onglyza An increased risk of hypoglycemia Details Fosinopril Semaglutide Ozempic An increased risk of hypoglycemia Details Fosinopril Sitagliptin Brynovin An increased risk of hypoglycemia Details Fosinopril Sodium Salicylate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Sulindac Clinoril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Tenoxicam Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Tiaprofenic Acid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Tolazamide Tolinase® An increased risk of hypoglycemia Details Fosinopril Tolbutamide Orinase® An increased risk of hypoglycemia Details Fosinopril Tolfenamic Acid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Tolmetin Tolectin 600 Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Torsemide Soaanz Postural hypotension (first dose) Details Fosinopril Trichlormethiazide Reduction of blood pressure Details Fosinopril Valdecoxib Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Xipamide Reduction of blood pressure Details Fosinopril Yohimbine Reduced angiotensin converting enzyme inhibitor effectiveness Details Fosinopril Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Fosinopril Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Fosinopril Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Fosinopril Ketorolac Injection Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Ketorolac Nasal Spray Sprix Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Ketorolac Ophthalmic Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Fosinopril Lanthanum Fosrenol® Reduced bioavailability of ACE inhibitors Details Fosinopril Liraglutide Injection Saxenda An increased risk of hypoglycemia Details Fosinopril Lixisenatide Injection Adlyxin® An increased risk of hypoglycemia Details Fosinopril Meloxicam Injection Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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