Gepotidacin

95 interactions 6 explained in plain English
Also sold as: Blujepa
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketoconazole Topical Nafcillin Injection Famotidine Injection Dihydroergotamine Injection Disopyramide Oxaliplatin Injection
1 Contraindicated 92 Major 2 Moderate
All (95) Contraindicated (1) Major (92) Moderate (2)

Major

Gepotidacin Moxifloxacin Injection Avelox An increased risk of QT interval prolongation Details Gepotidacin Moxifloxacin Ophthalmic Moxeza® An increased risk of QT interval prolongation Details Gepotidacin Nafarelin Nasal Spray Synarel An increased risk of QT interval prolongation Details Gepotidacin Nafcillin Injection Unipen® Injection Reduced gepotidacin exposure Details Gepotidacin Neratinib Nerlynx Increased CYP3A4 substrate with NTI exposure Details Gepotidacin Nifedipine Adalat® Increased NIFEdipine exposure Details Gepotidacin Octreotide Bynfezia An increased risk of QT interval prolongation Details Gepotidacin Octreotide Injection Bynfezia An increased risk of QT interval prolongation Details Gepotidacin Ofloxacin Floxin® An increased risk of QT interval prolongation Details Gepotidacin Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation Details Gepotidacin Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation Details Gepotidacin Olaparib Lynparza Increased CYP3A4 substrate with NTI exposure Details Gepotidacin Oxaliplatin Injection Eloxatin® An increased risk of QT interval prolongation Details

Moderate

Gepotidacin Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Gepotidacin Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.