Gilteritinib

Name: Gilteritinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

82 interactions 305 cited references

Also sold as: Xospata Xospata®

About Gilteritinib

Gilteritinib is used to treat a certain type of acute myeloid leukemia (AML) that has worsened or returned after treatment with other chemotherapy medications. Gilteritinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be neede… Read the full Gilteritinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

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10 Contraindicated 64 Major 8 Moderate

All (82) Contraindicated (10) Major (64) Moderate (8)

Moderate

Gilteritinib Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Gilteritinib Sparsentan Filspari Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse effects Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.