Glycopyrronium Tosylate

18 interactions 4 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Hydromorphone Rectal Glucagon Injection Glucagon Injection / Solution Glucagon Nasal Powder Hydromorphone Injection Ipratropium Oral Inhalation
18 Major
All (18) Major (18)

Major

Glycopyrronium Tosylate Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of paralytic ileus Details Glycopyrronium Tosylate Amitriptyline Elavil Explained An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Buprenorphine Belbuca Explained An increased risk of paralytic ileus Details Glycopyrronium Tosylate Trospium / Xanomeline Cobenfy Explained An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Aclidinium Oral Inhalation Tudorza An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Atropine Ophthalmic Atropine Care 1% An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Cyclopentolate Ophthalmic Akpentolate® An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Diphenhydramine Injection Banophen An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Diphenhydramine Topical Afterbite with Antihistamine An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Fentanyl Transdermal Patch Duragesic® Increased risk of urinary retention and/or severe constipation, which may lead to paralytic ileus Details Glycopyrronium Tosylate Glucagon Injection Baqsimi Increased risk of gastrointestinal side effects Details Glycopyrronium Tosylate Glucagon Injection / Solution Baqsimi Increased risk of gastrointestinal side effects Details Glycopyrronium Tosylate Glucagon Nasal Powder Baqsimi Increased risk of gastrointestinal side effects Details Glycopyrronium Tosylate Hydromorphone Injection Dilaudid Increased risk of urinary retention and/or severe constipation leading to paralytic ileus Details Glycopyrronium Tosylate Hydromorphone Rectal available generically Increased risk of urinary retention and/or severe constipation leading to paralytic ileus Details Glycopyrronium Tosylate Ipratropium Nasal Spray Atrovent Nasal Spray® An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Ipratropium Oral Inhalation Atrovent® HFA An increased risk of anticholinergic side effects Details Glycopyrronium Tosylate Morphine Injection Astramorph® PF Increased risk of urinary retention, severe constipation, and paralytic ileus Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.