Granisetron Transdermal Patch

281 interactions 403 cited references
Also sold as: Sancuso Sancuso®
About Granisetron Transdermal Patch

Granisetron transdermal patches are used to prevent nausea and vomiting caused by chemotherapy. Granisetron is in a class of medications called 5HT3 inhibitors. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting. Read the full Granisetron Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine
16 Contraindicated 265 Major
All (281) Contraindicated (16) Major (265)

Major

Granisetron Transdermal Patch Cocaine Goprelto Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Crizotinib Xalkori An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Cyclobenzaprine Amrix Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Dabrafenib Tafinlar An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Dasatinib Phyrago An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Degarelix Firmagon Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Delamanid Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Desflurane Suprane An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Desipramine Norpramin Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Desvenlafaxine Pristiq Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Dexmedetomidine Dexased Increased risk of cardiac arrhythmias Details Granisetron Transdermal Patch Dextroamphetamine Dexedrine An increased risk of serotonin syndrome Details Granisetron Transdermal Patch Dextromethorphan Delsym Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Dibenzepin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Difenoxin Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Dihydrocodeine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Diphenoxylate Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Disopyramide Norpace An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Dofetilide Tikosyn An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Dolasetron Anzemet Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Domperidone Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Donepezil Adlarity Increased risk of QT-interval prolongation and torsade de pointes Details Granisetron Transdermal Patch Dordaviprone An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Doxepin Prudoxin Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Droperidol An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Duloxetine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Efavirenz An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Eletriptan Relpax Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Encorafenib Braftovi Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Erythromycin Erythrocin Stearate Increased risk of QT interval prolongation Details Granisetron Transdermal Patch Escitalopram Lexapro Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Transdermal Patch Ethylmorphine Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Etrasimod Velsipity Increased risk of transient reduction in heart rate, AV conduction, QT interval prolongation and an increased risk of torsade de p... Details Granisetron Transdermal Patch Fenfluramine An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) Details Granisetron Transdermal Patch Fentanyl Increased risk of serotonin syndrome Details Granisetron Transdermal Patch Fexinidazole An increased risk of QT interval prolongation Details Granisetron Transdermal Patch Fingolimod Gilenya Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.