Grazoprevir

Name: Grazoprevir Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

28 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Fostemsavir Ketoconazole Topical Enasidenib Gemfibrozil Cyclosporine Injection Cyclosporine Ophthalmic

7 Contraindicated 14 Major 7 Moderate

All (28) Contraindicated (7) Major (14) Moderate (7)

Moderate

Grazoprevir Simvastatin Flolipid Explained Increased statin plasma concentrations Details Grazoprevir Dofetilide Tikosyn Increased dofetilide exposure Details Grazoprevir Encorafenib Braftovi Increased OATP1B1 substrate exposure, increased OATP1B3 substrate exposure, increased risk of OATP1B1 substrate-related toxicities... Details Grazoprevir Fluvastatin Lescol Increased statin plasma concentrations Details Grazoprevir Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Grazoprevir Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Grazoprevir Lovastatin Altocor® Increased statin plasma concentrations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.