Indapamide

102 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Rectal Fenoprofen Meloxicam Glipizide Mefenamic Acid Miglitol
54 Major 48 Moderate
All (102) Major (54) Moderate (48)

Major

Indapamide Liraglutide Injection Saxenda An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Lithium Carbonate Lithobid Increased lithium exposure and an increased risk of lithium toxicity (weakness, tremor, excessive thirst, confusion) Details Indapamide Lixisenatide Injection Adlyxin® An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Meclofenamate Meclodium® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Mefenamic Acid Ponstel® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Meloxicam Alloxate Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Meloxicam Injection Alloxate Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Indapamide Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Indapamide Miglitol Glyset® An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Morphine Injection Astramorph® PF Reduced efficacy of diuretics Details Indapamide Nabumetone Relafen Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Naproxen Aleve Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Nateglinide Starlix® An increased risk of hyperglycemia and an increased insulin requirement Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.