Insulin Degludec (Rdna Origin) Injection

Name: Insulin Degludec (Rdna Origin) Injection Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

166 interactions 217 cited references

Also sold as: Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Tresiba Tresiba® Xultophy® (as a combination product containing Insulin Degludec and Liraglutide)

About Insulin Degludec (Rdna Origin) Injection

Insulin degludec is used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). It is also used to treat people with type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amoun… Read the full Insulin Degludec (Rdna Origin) Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abiraterone Acetate Abiraterone Acetate, Micronized Acarbose Alogliptin Bromocriptine Canagliflozin

67 Major 99 Moderate

All (166) Major (67) Moderate (99)

Moderate

Insulin Degludec (Rdna Origin) Injection Telmisartan Micardis Increased risk of hypoglycemia Details Insulin Degludec (Rdna Origin) Injection Timolol Betimol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Insulin Degludec (Rdna Origin) Injection Tirzepatide Mounjaro Increased risk of hypoglycemia Details Insulin Degludec (Rdna Origin) Injection Trandolapril Mavik® An increased risk of hypoglycemia Details Insulin Degludec (Rdna Origin) Injection Tranylcypromine Parnate An increased risk of hypoglycemia Details Insulin Degludec (Rdna Origin) Injection Valsartan Diovan Increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.