Insulin

130 interactions 3 explained in plain English

Also sold as: Afrezza Humulin R Myxredlin Novolin R

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Miglitol Gemifloxacin Metoclopramide Injection Glipizide Moxifloxacin Injection Metoclopramide Nasal Spray

51 Major 79 Moderate

All (130) Major (51) Moderate (79)

Moderate

Insulin Flunisolide Nasal Spray Nasalide® Reduced blood glucose lowering effect of insulin Details Insulin Flunisolide Oral Inhalation AeroBid® Inhaler System Reduced blood glucose lowering effect of insulin Details Insulin Fluocinolone Capex Reduced blood glucose lowering effect of insulin Details Insulin Fluocinolone Topical Capex® Shampoo Reduced blood glucose lowering effect of insulin Details Insulin Fluocinonide Vanos Reduced blood glucose lowering effect of insulin Details Insulin Fluocinonide Topical Dermacin® Reduced blood glucose lowering effect of insulin Details Insulin Flurandrenolide Topical Cordran Reduced blood glucose lowering effect of insulin Details Insulin Fosinopril Monopril® An increased risk of hypoglycemia Details Insulin Gemfibrozil Lopid An increased risk of hypoglycemia Details Insulin Glucagon Injection Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Glucagon Injection / Solution Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Glucagon Nasal Powder Baqsimi Decreased blood glucose-lowering effects; interference with glucagon action Details Insulin Halcinonide Topical Halog Reduced blood glucose lowering effect of insulin Details Insulin Halobetasol Topical Duobrii (as a combination product containing Halobetasol, Tazarotene) Reduced blood glucose lowering effect of insulin Details Insulin Hydrocortisone Ala-Cort Reduced blood glucose lowering effect of insulin Details Insulin Hydrocortisone Injection A-Hydrocort® Reduced blood glucose lowering effect of insulin Details Insulin Irbesartan Avapro Increased risk of hypoglycemia Details Insulin Levonorgestrel After banger Reduced blood glucose lowering effect of insulin Details Insulin Levonorgestrel Intrauterine System Kyleena Reduced blood glucose lowering effect of insulin Details Insulin Levothyroxine Ermeza May decrease blood glucose lowering effect of insulin Details Insulin Linezolid Injection Zyvox An increased risk of hypoglycemia Details Insulin Liothyronine Cytomel May decrease blood glucose lowering effect of insulin Details Insulin Lithium Carbonate Lithobid Hypoglycemia or hyperglycemia Details Insulin Lixisenatide Injection Adlyxin® An increased risk of hypoglycemia Details Insulin Losartan Arbli Increased risk of hypoglycemia Details Insulin Loteprednol Etabonate Alrex Reduced blood glucose lowering effect of insulin Details Insulin Loteprednol Ophthalmic Alrex Reduced blood glucose lowering effect of insulin Details Insulin Medroxyprogesterone Amen® Reduced blood glucose lowering effect of insulin Details Insulin Medroxyprogesterone Injection Depo-Provera Reduced blood glucose lowering effect of insulin Details Insulin Mesalamine Apriso Increased risk of hypoglycemia Details Insulin Mesalamine Rectal Canasa Increased risk of hypoglycemia Details Insulin Moexipril Univasc® An increased risk of hypoglycemia Details Insulin Mometasone Asmanex Reduced blood glucose lowering effect of insulin Details Insulin Mometasone Nasal Spray Nasonex Reduced blood glucose lowering effect of insulin Details Insulin Mometasone Oral Inhalation Asmanex Reduced blood glucose lowering effect of insulin Details Insulin Mometasone Topical Elocon® Reduced blood glucose lowering effect of insulin Details Insulin Niacin Endur-Acin May decrease blood glucose lowering effect of insulin Details Insulin Olmesartan Benicar Increased risk of hypoglycemia Details Insulin Perindopril Aceon An increased risk of hypoglycemia Details

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