Irinotecan Lipid Complex Injection
73 interactions 335 cited references
Also sold as:
Onivyde®
Onpattro
About Irinotecan Lipid Complex Injection
Irinotecan lipid complex is used in combination with other medications to treat pancreatic cancer that has spread to other parts of the body that has worsened after treatment with other chemotherapy medications. Irinotecan lipid complex is in a class of antineoplastic medications called topoisomerase I inhibitors. It w… Read the full Irinotecan Lipid Complex Injection drug information page →
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Aug 9, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Yellow Fever Vaccine
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Dengue Tetravalent Vaccine, Live
Major
Irinotecan Lipid Complex Injection Mifepristone Korlym Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Mitotane Lysodren Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Nefazodone Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Nelfinavir Viracept Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Netupitant Increased exposure to chemotherapy agent and increased risk of side effects Details Irinotecan Lipid Complex Injection Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Irinotecan Lipid Complex Injection Paritaprevir Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Phenobarbital Fidoquel Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Irinotecan Lipid Complex Injection Phenytoin Dilantin Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Posaconazole Noxafil Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Primidone Mysoline Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Irinotecan Lipid Complex Injection Probenecid Increased irinotecan exposure and an increased irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Quizartinib Vanflyta Increased BCRP substrate exposure and an increased risk of BCRP substrate-related adverse reactions Details Irinotecan Lipid Complex Injection Relacorilant Lifyorli Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse reactions Details Irinotecan Lipid Complex Injection Ribociclib Kisqali Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Rifabutin Mycobutin Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Rifampin Rifadin Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Rifapentine Priftin Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Ritonavir Norvir Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Irinotecan Lipid Complex Injection Saquinavir Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection St John's Wort Reduced irinotecan exposure and reduced irinotecan active metabolite exposure Details Irinotecan Lipid Complex Injection Tazemetostat Tazverik Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Irinotecan Lipid Complex Injection Telaprevir Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Telithromycin Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Troleandomycin Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Tucatinib Tukysa Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure Details Irinotecan Lipid Complex Injection Voriconazole Vfend Increased irinotecan liposome exposure and an increased irinotecan liposome active metabolite exposure DetailsModerate
Irinotecan Lipid Complex Injection Artemether Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Irinotecan Lipid Complex Injection Kratom Increased CYP3A substrate exposure Details Irinotecan Lipid Complex Injection Mavacamten Camzyos Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Irinotecan Lipid Complex Injection Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Irinotecan Lipid Complex Injection Rolapitant Varubi Increased irinotecan exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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