Isavuconazole

Major

Isavuconazole Relugolix Orgovyx Explained Increased relugolix exposure Details Isavuconazole Atogepant Qulipta Reduced atogepant exposure Details Isavuconazole Avapritinib Ayvakit Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Isavuconazole Atorvastatin Atorvaliq Increased atorvastatin exposure Details Isavuconazole Cariprazine Vraylar Explained Increased cariprazine and its major active metabolite (didesmethylcariprazine (DDCAR)) exposure Details Isavuconazole Amlodipine Amvaz® Increased amLODIPine exposure, an increased risk of hypotension and edema and reduced amLODIPine exposure Details Isavuconazole Bedaquiline Sirturo Increased bedaquiline exposure Details Isavuconazole Brexpiprazole Rexulti Increased brexpiprazole exposure Details Isavuconazole Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Isavuconazole Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Isavuconazole Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Isavuconazole Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Isavuconazole Digoxin Cardoxin® Increased exposure of P-gp substrate Details Isavuconazole Dihydroergotamine Injection DHE-45® Injection Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Isavuconazole Dihydroergotamine Nasal Spray Migranal Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Isavuconazole Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Isavuconazole Enasidenib Idhifa Reduced antifungal exposure and reduced efficacy of antifungal agent Details Isavuconazole Encorafenib Braftovi Increased encorafenib exposure and an increased risk of encorafenib-related adverse events; reduced CYP3A4 substrate exposure and... Details Isavuconazole Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Isavuconazole Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions and increased isavuconazonium exposure a... Details Isavuconazole Lenacapavir Injection Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Isavuconazole Lenacapavir Oral Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Isavuconazole Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Isavuconazole Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Isavuconazole Lumateperone Caplyta Altered (reduced/increased) lumateperone exposure and an increased risk of lumateperone-related adverse reaction Details Isavuconazole Lurbinectedin Injection Zepzelca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Isavuconazole Metformin Fortamet® Increased metFORMIN exposure and an increased risk of lactic acidosis Details Isavuconazole Methylergonovine Methergine Increased methylergonovine exposure and an increased risk of vasospasm, cerebral ischemia and/or ischemia of extremities Details Isavuconazole Midazolam Nasal Spray Nayzilam Increased midazolam exposure Details Isavuconazole Midazolam Injection Nayzilam Increased midazolam exposure Details Isavuconazole Mitapivat Aqvesme Increased mitapivat exposure and reduced CYP3A4 substrate exposure Details Isavuconazole Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Isavuconazole Nifedipine Adalat® Increased NIFEdipine exposure and reduced NIFEdipine exposure Details