Ketorolac Ophthalmic

Name: Ketorolac Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

246 interactions 464 cited references

Also sold as: Acular Acular® Acuvail Acuvail®

About Ketorolac Ophthalmic

Ophthalmic ketorolac is used to treat itchy eyes caused by allergies. It also is used to treat swelling and redness (inflammation) that can occur after cataract surgery. Ketorolac is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the release of substances that cause… Read the full Ketorolac Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Fenoprofen Flurbiprofen Fepradinol Feprazone Floctafenine Flufenamic Acid

64 Contraindicated 129 Major 53 Moderate

All (246) Contraindicated (64) Major (129) Moderate (53)

Major

Ketorolac Ophthalmic Trichlormethiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Trimipramine An increased risk of bleeding Details Ketorolac Ophthalmic Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details Ketorolac Ophthalmic Venlafaxine An increased risk of bleeding Details Ketorolac Ophthalmic Vilazodone Viibryd An increased risk of bleeding Details Ketorolac Ophthalmic Vorapaxar Zontivity An increased risk of bleeding Details Ketorolac Ophthalmic Vortioxetine Trintellix An increased risk of bleeding Details Ketorolac Ophthalmic Warfarin Coumadin An increased risk of bleeding Details Ketorolac Ophthalmic Xipamide Reduced diuretic effectiveness and possible nephrotoxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.