Ketorolac Ophthalmic

246 interactions 464 cited references

Also sold as: Acular Acular® Acuvail Acuvail®

About Ketorolac Ophthalmic

Ophthalmic ketorolac is used to treat itchy eyes caused by allergies. It also is used to treat swelling and redness (inflammation) that can occur after cataract surgery. Ketorolac is in a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by stopping the release of substances that cause… Read the full Ketorolac Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Fenoprofen Flurbiprofen Fepradinol Feprazone Floctafenine Flufenamic Acid

64 Contraindicated 129 Major 53 Moderate

All (246) Contraindicated (64) Major (129) Moderate (53)

Major

Ketorolac Ophthalmic Abciximab An increased risk of bleeding Details Ketorolac Ophthalmic Acenocoumarol An increased risk of bleeding Details Ketorolac Ophthalmic Amiloride Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Ketorolac Ophthalmic Amineptine An increased risk of bleeding Details Ketorolac Ophthalmic Amitriptyline Elavil An increased risk of bleeding Details Ketorolac Ophthalmic Amitriptylinoxide An increased risk of bleeding Details Ketorolac Ophthalmic Amoxapine An increased risk of bleeding Details Ketorolac Ophthalmic Anagrelide Agrylin An increased risk of bleeding Details Ketorolac Ophthalmic Apixaban Eliquis An increased risk of bleeding Details Ketorolac Ophthalmic Ardeparin An increased risk of bleeding Details Ketorolac Ophthalmic Argatroban An increased risk of bleeding Details Ketorolac Ophthalmic Bemetizide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Bemiparin An increased risk of bleeding Details Ketorolac Ophthalmic Bendroflumethiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Benzthiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Betrixaban Bevyxxa® An increased risk of bleeding Details Ketorolac Ophthalmic Bivalirudin Angiomax An increased risk of bleeding Details Ketorolac Ophthalmic Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Ketorolac Ophthalmic Bumetanide Bumex Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Cangrelor Kengreal An increased risk of bleeding Details Ketorolac Ophthalmic Certoparin An increased risk of bleeding Details Ketorolac Ophthalmic Chlorothiazide Diuril Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Chlorthalidone Hemiclor Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Cilostazol Pletal® An increased risk of bleeding Details Ketorolac Ophthalmic Citalopram Celexa An increased risk of bleeding Details Ketorolac Ophthalmic Clomipramine Anafranil An increased risk of bleeding Details Ketorolac Ophthalmic Clopamide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Clopidogrel Plavix An increased risk of bleeding Details Ketorolac Ophthalmic Cyclopenthiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Cyclosporine Atopica An increased risk of cycloSPORINE nephrotoxicity Details Ketorolac Ophthalmic Cyclothiazide Reduced diuretic effectiveness and possible nephrotoxicity Details Ketorolac Ophthalmic Dabigatran Etexilate An increased risk of bleeding Details Ketorolac Ophthalmic Dalteparin Fragmin An increased risk of bleeding Details Ketorolac Ophthalmic Danaparoid An increased risk of bleeding Details Ketorolac Ophthalmic Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Ketorolac Ophthalmic Desipramine Norpramin An increased risk of bleeding Details Ketorolac Ophthalmic Desirudin Iprivask An increased risk of bleeding Details Ketorolac Ophthalmic Desvenlafaxine Pristiq An increased risk of bleeding Details Ketorolac Ophthalmic Dexamethasone Increased risk of gastrointestinal ulcer or bleeding Details Ketorolac Ophthalmic Diazoxide Proglycem Reduced diuretic effectiveness and possible nephrotoxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.