Ketotifen Ophthalmic

Name: Ketotifen Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions 133 cited references

Also sold as: Alaway Alaway® Claritin Eye Wal-Zyr Itchy Eye Zaditor Zaditor®

About Ketotifen Ophthalmic

Ophthalmic ketotifen is used to relieve the itching of allergic pinkeye. Ketotifen is in a class of medications called antihistamines. It works by blocking histamine, a substance in the body that causes allergic symptoms. Read the full Ketotifen Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Tranylcypromine Amifampridine Bupropion Clomipramine Donepezil Hydroxychloroquine

1 Contraindicated 7 Major

All (8) Contraindicated (1) Major (7)

Major

Ketotifen Ophthalmic Amifampridine Increased risk of seizures Details Ketotifen Ophthalmic Bupropion Aplenzin Increased risk of seizures Details Ketotifen Ophthalmic Clomipramine Anafranil Increased risk of seizures Details Ketotifen Ophthalmic Donepezil Adlarity Reduced seizure threshold Details Ketotifen Ophthalmic Hydroxychloroquine Plaquenil An increased risk of seizures Details Ketotifen Ophthalmic Pitolisant Wakix Reduced efficacy of pitolisant Details Ketotifen Ophthalmic Tramadol ConZip An increased risk of seizure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.