Levoketoconazole

185 interactions 11 explained in plain English

Also sold as: Recorlev Recorlev®

About Levoketoconazole

Levoketoconazole is used to treat high levels of cortisol (a hormone produced by your adrenal glands) in patients with Cushing's syndrome (a condition in which the body produces too much cortisol) and who have failed surgery or cannot have surgery to treat this condition. Levoketoconazole is in a class of medications c… Read the full Levoketoconazole drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metronidazole Injection Mefloquine Hydroxychloroquine Oxaliplatin Injection Clindamycin Topical Chloroquine

103 Contraindicated 82 Major

All (185) Contraindicated (103) Major (82)

Major

Levoketoconazole Abacavir Ziagen Explained Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Omeprazole Gastrobim Explained Reduced levoketoconazole exposure Details Levoketoconazole Acarbose Prandase® Explained Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Acetazolamide Diamox® Sequels® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Adalimumab Injection Abrilada Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Albendazole Albendamax Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Allopurinol Aloprim Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Allopurinol Injection Aloprim Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Ambrisentan Letairis Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Atovaquone Mepron Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Azacitidine Onureg Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Bicalutamide Casodex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Atorvastatin Atorvaliq Increased atorvastatin exposure and an increased risk of atorvastatin-related adverse effects Details Levoketoconazole Azacitidine Injection Onureg Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Bexarotene Targretin Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Bexarotene Topical Targretin Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Bortezomib Boruzu Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Busulfan Injection Busulfex Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Captopril Capoten® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Caspofungin Injection Cancidas Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Cefadroxil Duricef® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Cefdinir Omnicef® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Clofarabine Injection Clolar Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Clopidogrel Plavix Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Dactinomycin Cosmegen Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Danazol Danocrine® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Deferasirox Exjade Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Dexlansoprazole Dexilant Reduced levoketoconazole exposure Details Levoketoconazole Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Diclofenac Transdermal Patch Flector Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Disulfiram Antabuse Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Enalapril Epaned Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Entecavir Baraclude Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Epoprostenol Flolan Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Erlotinib Tarceva Increased risk of serious hepatotoxicity and drug-induced liver injury Details Levoketoconazole Esomeprazole Nexium Reduced levoketoconazole exposure Details Levoketoconazole Esomeprazole Injection Nexium Reduced levoketoconazole exposure Details Levoketoconazole Ethambutol Myambutol Increased risk of serious hepatotoxicity and drug-induced liver injury Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.