Lumiracoxib
91 interactions 5 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketorolac
Ketorolac Ophthalmic
Ketorolac Nasal Spray
Ketorolac Injection
Diclofenac Ophthalmic
Pemetrexed Injection
Major
Lumiracoxib Fondaparinux Injection Arixtra An increased risk of bleeding Details Lumiracoxib Furosemide Injection Disal Reduced diuretic effectiveness and possible nephrotoxicity Details Lumiracoxib Heparin An increased risk of bleeding Details Lumiracoxib Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Lumiracoxib Hydrocortisone Ala-Cort Increased risk of gastrointestinal ulcer or bleeding Details Lumiracoxib Hydrocortisone Injection A-Hydrocort® Increased risk of gastrointestinal ulcer or bleeding Details Lumiracoxib Ibuprofen Addaprin An increased risk of gastrointestinal toxicity Details Lumiracoxib Iloprost Aurlumyn An increased risk of bleeding Details Lumiracoxib Ketoprofen Actron® Increased risk of bleeding Details Lumiracoxib Lithium Carbonate Lithobid Increased lithium exposure and an increased risk of lithium toxicity Details Lumiracoxib Meclofenamate Meclodium® Increased risk of bleeding Details Lumiracoxib Mefenamic Acid Ponstel® Increased risk of bleeding Details Lumiracoxib Meloxicam Alloxate Increased risk of bleeding Details Lumiracoxib Meloxicam Injection Alloxate Increased risk of bleeding Details Lumiracoxib Melphalan Alkeran An increased risk of bleeding Details Lumiracoxib Melphalan Injection Alkeran An increased risk of bleeding Details Lumiracoxib Mesalamine Apriso Increased risk of bleeding Details Lumiracoxib Mesalamine Rectal Canasa Increased risk of bleeding Details Lumiracoxib Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Lumiracoxib Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Lumiracoxib Nabumetone Relafen Increased risk of bleeding Details Lumiracoxib Naproxen Aleve Increased risk of bleeding Details Lumiracoxib Pemetrexed Injection Alimta Increased PEMEtrexed exposure and an increased risk of PEMEtrexed toxicity (myelosuppression, renal toxicity, and gastrointestinal... DetailsModerate
Lumiracoxib Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Atenolol Tenormin Explained Reduced antihypertensive effect Details Lumiracoxib Acebutolol Sectral® Reduced antihypertensive effect Details Lumiracoxib Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Betaxolol Betoptic S Reduced antihypertensive effect Details Lumiracoxib Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Lumiracoxib Bisoprolol Zebeta® Reduced antihypertensive effect Details Lumiracoxib Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Lumiracoxib Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Esmolol Brevibloc Reduced antihypertensive effect Details Lumiracoxib Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Labetalol Normodyne® Reduced antihypertensive effect Details Lumiracoxib Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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