Lumiracoxib

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Ketorolac Ophthalmic Ketorolac Nasal Spray Ketorolac Injection Diclofenac Ophthalmic Pemetrexed Injection
4 Contraindicated 59 Major 28 Moderate
All (91) Contraindicated (4) Major (59) Moderate (28)

Moderate

Lumiracoxib Lisinopril Prinivil Explained Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Atenolol Tenormin Explained Reduced antihypertensive effect Details Lumiracoxib Acebutolol Sectral® Reduced antihypertensive effect Details Lumiracoxib Benazepril Lotensin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Azilsartan Edarbi Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Betaxolol Betoptic S Reduced antihypertensive effect Details Lumiracoxib Betaxolol Ophthalmic Betoptic® Reduced antihypertensive effect Details Lumiracoxib Bisoprolol Zebeta® Reduced antihypertensive effect Details Lumiracoxib Captopril Capoten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details Lumiracoxib Enalapril Epaned Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Eprosartan Teveten® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Esmolol Brevibloc Reduced antihypertensive effect Details Lumiracoxib Fosinopril Monopril® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Irbesartan Avapro Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Labetalol Normodyne® Reduced antihypertensive effect Details Lumiracoxib Levobunolol Ophthalmic AKBeta® Reduced antihypertensive effect Details Lumiracoxib Levofloxacin Levaquin An increased risk of seizures Details Lumiracoxib Levofloxacin Injection Levaquin An increased risk of seizures Details Lumiracoxib Losartan Arbli Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Moexipril Univasc® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Lumiracoxib Nadolol Corgard Reduced antihypertensive effect Details Lumiracoxib Nebivolol Bystolic Reduced antihypertensive effect Details Lumiracoxib Ofloxacin Floxin® An increased risk of seizures Details Lumiracoxib Ofloxacin Ophthalmic Ocuflox An increased risk of seizures Details Lumiracoxib Ofloxacin Otic Floxin® Otic An increased risk of seizures Details Lumiracoxib Penbutolol Levatol® Reduced antihypertensive effect Details Lumiracoxib Perindopril Aceon Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.