Meprobamate

21 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Levodopa Oral Inhalation Metoclopramide Nasal Spray Nalbuphine Injection Cetirizine Injection Hydromorphone Injection
20 Major 1 Moderate
All (21) Major (20) Moderate (1)

Major

Meprobamate Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Meprobamate Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Meprobamate Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Meprobamate Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Meprobamate Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Meprobamate Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Meprobamate Diazepam Nasal Spray Valtoco Additive respiratory depression Details Meprobamate Diazepam Rectal Diastat Additive respiratory depression Details Meprobamate Esketamine Nasal Spray Spravato Increased risk of sedation Details Meprobamate Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Meprobamate Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Meprobamate Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Meprobamate Lacosamide Injection Motpoly An increased risk of CNS depression Details Meprobamate Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Meprobamate Metoclopramide Injection Gimoti Increased risk of CNS depression Details Meprobamate Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Meprobamate Midazolam Nasal Spray Nayzilam Additive respiratory depression Details Meprobamate Midazolam Injection Nayzilam Additive respiratory depression Details Meprobamate Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Meprobamate Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.