Methotrexate Injection
354 interactions 996 cited referencesMethotrexate injection is used alone or in combination with other medications: to treat certain types of acute lymphocytic leukemia (ALL) in adults and children; to treat or prevent meningeal leukemia (cancer in the covering of the spinal cord and brain) in adults and children; to treat certain types of non-Hodgkin's l… Read the full Methotrexate Injection drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
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Methotrexate Injection Capecitabine Xeloda Increased 5-fluorouracil toxicity Details Methotrexate Injection Capmatinib Tabrecta Increased BCRP substrate exposure and an increased risk of adverse reactions Details Methotrexate Injection Captopril Capoten® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Carbamazepine Carbatrol Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Caspofungin Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefaclor Ceclor® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefadroxil Duricef® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefdinir Omnicef® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefixime Suprax Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefprozil Cefzil® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cefuroxime Ceftin® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Celecoxib Celebrex Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cephalexin Keflet® Tablets Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chenodiol Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chloral Hydrate Increased methotrexate exposure Details Methotrexate Injection Chloramphenicol Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chlorpropamide Diabinese® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chlortetracycline Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chlorthalidone Hemiclor Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Chlorzoxazone Lorzone Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Methotrexate Injection Choline Salicylate Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Ciprofloxacin Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Citalopram Celexa Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clarithromycin Biaxin Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clindamycin ANTIROBE Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clofarabine Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clomipramine Anafranil Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clonixin Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Clopidogrel Plavix Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cloxacillin Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Cyclosporine Atopica Increased methotrexate exposure, potentiation of methotrexate efficacy, methotrexate toxicity or methotrexate-related severe adver... Details Methotrexate Injection Cyproheptadine Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Dabigatran Etexilate Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Dactinomycin Cosmegen Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Danazol Danocrine® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Danicopan Voydeya Increased BCRP substrate exposure and an increased risk of BCRP substrate-related adverse effect Details Methotrexate Injection Dantrolene Dantrium Increased methotrexate exposure, an increased risk of methotrexate toxicity or methotrexate-related severe adverse reactions, redu... Details Methotrexate Injection Dapsone Aczone Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Methotrexate Injection Darolutamide Nubeqa Increased plasma concentrations of BCRP substrates DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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