Metronidazole

278 interactions 832 cited references

Also sold as: Flagyl Flagyl® Flagyl® 375 Flagyl® ER Likmez MetroCream MetroGel MetroLotion Noritate Nuvessa Nydamax Rosadan Vandazole

About Metronidazole

Metronidazole is an antibiotic used to treat bacterial and parasitic infections in various parts of the body, including the reproductive and gastrointestinal systems. Read the full Metronidazole drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Terfenadine Saquinavir Piperaquine Pimozide Thioridazine Sparfloxacin

15 Contraindicated 244 Major 19 Moderate

All (278) Contraindicated (15) Major (244) Moderate (19)

Major

Metronidazole Ozanimod Additive effects on heart rate Details Metronidazole Pacritinib Vonjo® An increased risk of QT interval prolongation Details Metronidazole Paliperidone Erzofri An increased risk of QT interval prolongation Details Metronidazole Panobinostat Farydak Increased risk of QT interval prolongation Details Metronidazole Papaverine Pavacot® An increased risk of QT interval prolongation Details Metronidazole Paroxetine Paxil An increased risk of QT interval prolongation Details Metronidazole Pasireotide Signifor An increased risk of QT interval prolongation Details Metronidazole Pazopanib Votrient An increased risk of QT-interval prolongation Details Metronidazole Pentamidine NebuPent An increased risk of QT interval prolongation Details Metronidazole Perphenazine An increased risk of QT interval prolongation Details Metronidazole Phenobarbital Fidoquel An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details Metronidazole Phenprocoumon An increased risk of bleeding Details Metronidazole Phenytoin Dilantin An increased risk of phenytoin toxicity or reduced metroNIDAZOLE exposure Details Metronidazole Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Metronidazole Pipamperone An increased risk of QT interval prolongation Details Metronidazole Pitolisant Wakix Increased risk of QT interval prolongation Details Metronidazole Ponesimod Ponvory An increased risk of QT interval prolongation Details Metronidazole Posaconazole Noxafil An increased risk of QT interval prolongation Details Metronidazole Primidone Mysoline An increased risk of QT interval prolongation, reduced metroNIDAZOLE exposure and reduced metroNIDAZOLE efficacy Details Metronidazole Probucol An increased risk of QT interval prolongation Details Metronidazole Procainamide Procan® An increased risk of QT interval prolongation Details Metronidazole Prochlorperazine An increased risk of QT interval prolongation Details Metronidazole Promethazine Phenadoz An increased risk of QT interval prolongation Details Metronidazole Propafenone Rythmol An increased risk of QT interval prolongation Details Metronidazole Protriptyline An increased risk of QT interval prolongation Details Metronidazole Quetiapine Seroquel An increased risk of QT interval prolongation Details Metronidazole Quinidine Cardioquin® An increased risk of QT interval prolongation Details Metronidazole Quinine An increased risk of QT interval prolongation Details Metronidazole Quizartinib Vanflyta An increased risk of QT interval prolongation Details Metronidazole Ranolazine Aspruzyo An increased risk of QT interval prolongation Details Metronidazole Revumenib Revuforj An increased risk of QT interval prolongation Details Metronidazole Ribociclib Kisqali An increased risk of QT interval prolongation Details Metronidazole Rilpivirine Edurant An increased risk of QT interval prolongation and torsade de pointes Details Metronidazole Risperidone Perseris An increased risk of QT interval prolongation Details Metronidazole Ritonavir Norvir An increased risk of QT interval prolongation Details Metronidazole Selpercatinib Retevmo Increased risk of QT interval prolongation Details Metronidazole Sertindole An increased risk of QT interval prolongation Details Metronidazole Sevoflurane Petrem An increased risk of QT interval prolongation Details Metronidazole Siponimod Mayzent An increased risk of QT interval prolongation Details Metronidazole Sodium Phosphate OsmoPrep An increased risk of QT interval prolongation Details

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